Matches in SemOpenAlex for { <https://semopenalex.org/work/W33446039> ?p ?o ?g. }
- W33446039 endingPage "4180" @default.
- W33446039 startingPage "4174" @default.
- W33446039 abstract "Duplications and interchromosomal transpositions of chromosome segments are implicated in the genetic variability of Plasmodium falciparum malaria parasites. One parasite clone, HB3, was shown to lack a subtelomeric region of chromosome 13 that normally carries a PfHRPIII gene. We show here that the chromosome 13 segment carrying PfHRPIII was replaced in HB3 by a duplicated terminal segment from chromosome 11. Mapping results indicate that the segment includes at least 100-200 kb of subtelomeric DNA and contains duplicated copies of the Pf332 and RESA-2 genes. We followed inheritance of this duplication in a genetic cross between the HB3 and another P.falciparum clone, Dd2, that is euploid for the Pf332, RESA-2 and PfHRPIII genes. Three types of progeny from the cross showed expected inheritance forms: a Dd2 euploid parent type, an HB3 aneuploid parent type, and a recombinant euploid type that carried PfHRPIII from Dd2 chromosome 13 and Pf332 from HB3 chromosome 11. However, a fourth euploid progeny type was also observed, in which the chromosome 13 segment from HB3 was transposed back to replace the terminus of chromosome 11. Three of 14 individual progeny were of this type. These findings suggest a mechanism of recombination from subtelomeric pairing and exchange between non-homologous chromosomes in meiosis." @default.
- W33446039 created "2016-06-24" @default.
- W33446039 creator A5035939794 @default.
- W33446039 creator A5059545052 @default.
- W33446039 creator A5067549205 @default.
- W33446039 creator A5070125689 @default.
- W33446039 date "1994-09-01" @default.
- W33446039 modified "2023-10-15" @default.
- W33446039 title "Interchromosomal exchange of a large subtelomeric segment in a Plasmodium falciparum cross." @default.
- W33446039 cites W167254290 @default.
- W33446039 cites W1758042697 @default.
- W33446039 cites W179409290 @default.
- W33446039 cites W1908670026 @default.
- W33446039 cites W1963787703 @default.
- W33446039 cites W1969503178 @default.
- W33446039 cites W1980752431 @default.
- W33446039 cites W1987862565 @default.
- W33446039 cites W1996090259 @default.
- W33446039 cites W2001102860 @default.
- W33446039 cites W2003069768 @default.
- W33446039 cites W2003977946 @default.
- W33446039 cites W2004296831 @default.
- W33446039 cites W2012812624 @default.
- W33446039 cites W2018057432 @default.
- W33446039 cites W2020637870 @default.
- W33446039 cites W2022713916 @default.
- W33446039 cites W2022865656 @default.
- W33446039 cites W2024411976 @default.
- W33446039 cites W2037244315 @default.
- W33446039 cites W2044099644 @default.
- W33446039 cites W2044973494 @default.
- W33446039 cites W2059661211 @default.
- W33446039 cites W2060358284 @default.
- W33446039 cites W2062303707 @default.
- W33446039 cites W2062395030 @default.
- W33446039 cites W2066291099 @default.
- W33446039 cites W2066686101 @default.
- W33446039 cites W2069670229 @default.
- W33446039 cites W2075392416 @default.
- W33446039 cites W2076854208 @default.
- W33446039 cites W2077164075 @default.
- W33446039 cites W2084850029 @default.
- W33446039 cites W2090082914 @default.
- W33446039 cites W2103884702 @default.
- W33446039 cites W2105939757 @default.
- W33446039 cites W2109816065 @default.
- W33446039 cites W2114934780 @default.
- W33446039 cites W2147775888 @default.
- W33446039 cites W2152170859 @default.
- W33446039 cites W2154751623 @default.
- W33446039 cites W2156932941 @default.
- W33446039 cites W2405643465 @default.
- W33446039 cites W76589491 @default.
- W33446039 doi "https://doi.org/10.1002/j.1460-2075.1994.tb06735.x" @default.
- W33446039 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/395340" @default.
- W33446039 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8076613" @default.
- W33446039 hasPublicationYear "1994" @default.
- W33446039 type Work @default.
- W33446039 sameAs 33446039 @default.
- W33446039 citedByCount "53" @default.
- W33446039 countsByYear W334460392012 @default.
- W33446039 countsByYear W334460392013 @default.
- W33446039 countsByYear W334460392014 @default.
- W33446039 countsByYear W334460392015 @default.
- W33446039 countsByYear W334460392022 @default.
- W33446039 crossrefType "journal-article" @default.
- W33446039 hasAuthorship W33446039A5035939794 @default.
- W33446039 hasAuthorship W33446039A5059545052 @default.
- W33446039 hasAuthorship W33446039A5067549205 @default.
- W33446039 hasAuthorship W33446039A5070125689 @default.
- W33446039 hasBestOaLocation W334460391 @default.
- W33446039 hasConcept C104317684 @default.
- W33446039 hasConcept C143191323 @default.
- W33446039 hasConcept C148196450 @default.
- W33446039 hasConcept C153911025 @default.
- W33446039 hasConcept C163588314 @default.
- W33446039 hasConcept C177658893 @default.
- W33446039 hasConcept C23069440 @default.
- W33446039 hasConcept C30481170 @default.
- W33446039 hasConcept C47924181 @default.
- W33446039 hasConcept C54355233 @default.
- W33446039 hasConcept C64894306 @default.
- W33446039 hasConcept C7602840 @default.
- W33446039 hasConcept C86803240 @default.
- W33446039 hasConceptScore W33446039C104317684 @default.
- W33446039 hasConceptScore W33446039C143191323 @default.
- W33446039 hasConceptScore W33446039C148196450 @default.
- W33446039 hasConceptScore W33446039C153911025 @default.
- W33446039 hasConceptScore W33446039C163588314 @default.
- W33446039 hasConceptScore W33446039C177658893 @default.
- W33446039 hasConceptScore W33446039C23069440 @default.
- W33446039 hasConceptScore W33446039C30481170 @default.
- W33446039 hasConceptScore W33446039C47924181 @default.
- W33446039 hasConceptScore W33446039C54355233 @default.
- W33446039 hasConceptScore W33446039C64894306 @default.
- W33446039 hasConceptScore W33446039C7602840 @default.
- W33446039 hasConceptScore W33446039C86803240 @default.
- W33446039 hasIssue "17" @default.