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- W336749488 abstract "Experiments were carried out to determine the mechanism involved in C3 breakdown by a factor (C3 nephritic factor - C3NeF) present in the serum of patients with hypocomplementaemic mesangiocapillary glomerulonephritis. The reaction was shown to depend upon the C3b feedback cycle and a protein bound by cobra venom factor was required. This protein (cobra binding protein) was distinct from GBG, and was also required for activation of the C3b feedback by inulin. C3NeF did not require detectable quantities of properdin to cause C3 breakdown in vitro, although there is good evidence that properdin is involved in this type of nephritis." @default.
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- W336749488 date "1974-01-01" @default.
- W336749488 modified "2023-09-23" @default.
- W336749488 title "Mechanisms of C3 Breakdown by Hypocomplementaemic Serum from Patients with Mesangiocapillary Nephritis" @default.
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- W336749488 doi "https://doi.org/10.1016/b978-0-08-017822-6.50073-3" @default.
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