Matches in SemOpenAlex for { <https://semopenalex.org/work/W337781569> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W337781569 endingPage "156" @default.
- W337781569 startingPage "143" @default.
- W337781569 abstract "Increased superoxide (O2 •−) and nitric oxide (NO) production is a key mechanism of mitochondrial dysfunction in myocardial ischemia/reperfusion injury. In the complex II, oxidative impairment, decreased protein S-glutathionylation, and increased protein tyrosine nitration at the 70 kDa subunit occur in the post-ischemic myocardium (Zhang et al., Biochemistry 49:2529–2539, 2010; Chen et al., J Biol Chem 283:27991–28003, 2008; Chen et al., J Biol Chem 282: 32640–32654, 2007). To gain the deeper insights into ROS-mediated oxidative modifications relevant in myocardial infarction, isolated complex II is subjected to in vitro oxidative modifications with GSSG (to induce cysteine S-glutathionylation) or OONO− (to induce tyrosine nitration). Here, we describe the protocol to characterize the specific oxidative modifications at the 70 kDa subunit by nano-LC/MS/MS analysis. We further demonstrate the cellular oxidative modification with protein nitration/S-glutathionylation with immunofluorescence microscopy using the antibodies against 3-nitrotyrosine/glutathione and complex II 70 kDa polypeptide (AbGSC90) in myocytes under conditions of oxidative stress." @default.
- W337781569 created "2016-06-24" @default.
- W337781569 creator A5013944424 @default.
- W337781569 creator A5037570579 @default.
- W337781569 creator A5056900404 @default.
- W337781569 creator A5060000124 @default.
- W337781569 creator A5089402019 @default.
- W337781569 date "2013-01-01" @default.
- W337781569 modified "2023-10-18" @default.
- W337781569 title "Oxidative Modifications of Mitochondria Complex II" @default.
- W337781569 cites W1482087680 @default.
- W337781569 cites W1965759525 @default.
- W337781569 cites W2002120674 @default.
- W337781569 cites W2040320750 @default.
- W337781569 cites W2041834967 @default.
- W337781569 cites W2067580720 @default.
- W337781569 cites W2080418501 @default.
- W337781569 cites W2090818200 @default.
- W337781569 cites W2093687559 @default.
- W337781569 cites W2113425981 @default.
- W337781569 doi "https://doi.org/10.1007/978-1-62703-386-2_12" @default.
- W337781569 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3774787" @default.
- W337781569 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23606255" @default.
- W337781569 hasPublicationYear "2013" @default.
- W337781569 type Work @default.
- W337781569 sameAs 337781569 @default.
- W337781569 citedByCount "8" @default.
- W337781569 countsByYear W3377815692013 @default.
- W337781569 countsByYear W3377815692015 @default.
- W337781569 countsByYear W3377815692019 @default.
- W337781569 countsByYear W3377815692021 @default.
- W337781569 countsByYear W3377815692022 @default.
- W337781569 countsByYear W3377815692023 @default.
- W337781569 crossrefType "book-chapter" @default.
- W337781569 hasAuthorship W337781569A5013944424 @default.
- W337781569 hasAuthorship W337781569A5037570579 @default.
- W337781569 hasAuthorship W337781569A5056900404 @default.
- W337781569 hasAuthorship W337781569A5060000124 @default.
- W337781569 hasAuthorship W337781569A5089402019 @default.
- W337781569 hasBestOaLocation W3377815692 @default.
- W337781569 hasConcept C104292427 @default.
- W337781569 hasConcept C104317684 @default.
- W337781569 hasConcept C178790620 @default.
- W337781569 hasConcept C181199279 @default.
- W337781569 hasConcept C185592680 @default.
- W337781569 hasConcept C2775856698 @default.
- W337781569 hasConcept C2776151105 @default.
- W337781569 hasConcept C2776165026 @default.
- W337781569 hasConcept C2777622882 @default.
- W337781569 hasConcept C2779201268 @default.
- W337781569 hasConcept C2779385521 @default.
- W337781569 hasConcept C2780795997 @default.
- W337781569 hasConcept C28859421 @default.
- W337781569 hasConcept C48349386 @default.
- W337781569 hasConcept C519581460 @default.
- W337781569 hasConcept C55493867 @default.
- W337781569 hasConcept C57600042 @default.
- W337781569 hasConceptScore W337781569C104292427 @default.
- W337781569 hasConceptScore W337781569C104317684 @default.
- W337781569 hasConceptScore W337781569C178790620 @default.
- W337781569 hasConceptScore W337781569C181199279 @default.
- W337781569 hasConceptScore W337781569C185592680 @default.
- W337781569 hasConceptScore W337781569C2775856698 @default.
- W337781569 hasConceptScore W337781569C2776151105 @default.
- W337781569 hasConceptScore W337781569C2776165026 @default.
- W337781569 hasConceptScore W337781569C2777622882 @default.
- W337781569 hasConceptScore W337781569C2779201268 @default.
- W337781569 hasConceptScore W337781569C2779385521 @default.
- W337781569 hasConceptScore W337781569C2780795997 @default.
- W337781569 hasConceptScore W337781569C28859421 @default.
- W337781569 hasConceptScore W337781569C48349386 @default.
- W337781569 hasConceptScore W337781569C519581460 @default.
- W337781569 hasConceptScore W337781569C55493867 @default.
- W337781569 hasConceptScore W337781569C57600042 @default.
- W337781569 hasLocation W3377815691 @default.
- W337781569 hasLocation W3377815692 @default.
- W337781569 hasLocation W3377815693 @default.
- W337781569 hasLocation W3377815694 @default.
- W337781569 hasOpenAccess W337781569 @default.
- W337781569 hasPrimaryLocation W3377815691 @default.
- W337781569 hasRelatedWork W1579340457 @default.
- W337781569 hasRelatedWork W1992054235 @default.
- W337781569 hasRelatedWork W2046122050 @default.
- W337781569 hasRelatedWork W2057348238 @default.
- W337781569 hasRelatedWork W2120278390 @default.
- W337781569 hasRelatedWork W2128022125 @default.
- W337781569 hasRelatedWork W2388113882 @default.
- W337781569 hasRelatedWork W2408313183 @default.
- W337781569 hasRelatedWork W2417394622 @default.
- W337781569 hasRelatedWork W2768547220 @default.
- W337781569 isParatext "false" @default.
- W337781569 isRetracted "false" @default.
- W337781569 magId "337781569" @default.
- W337781569 workType "book-chapter" @default.