FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W338184868> ?p ?o ?g. }

• W338184868 abstract "Abstract We studied whether treatment of dogs with recombinant human granulocyte colony-stimulating factor (rhG-CSF), after 920 cGy total body irradiation (TBI) and transplantation of 3.3 +/- 1.0 x 10(8) bone marrow cells per kilogram from a DLA-identical littermate, accelerated hematopoietic recovery and influenced the incidence of subsequent marrow graft failure or graft-versus-host disease (GVHD). Ten animals were treated with 100 micrograms rhG-CSF/kg/d from days 1 through 10 after TBI. Results were compared with those of historical control of 14 dogs not administered rhG-CSF. Neither group of dogs received GVHD prophylaxis. The median time to recovery of 1,000 neutrophils/mm3 was 8 days for dogs administered rhG-CSF compared with 14 days in controls (logrank test: P less than .03). The median time to reach 100 monocytes/mm3 was 17 days in G-CSF-treated dogs compared with 49 days in controls (P less than .002). The median time to attain 500 lymphocytes/mm3 was 15 days versus 31 days, respectively (P less than .01). The median time to reach 20,000 platelets/mm3 was 26 versus 20 days (P = .68). Graft failure occurred in 1 of 10 G-CSF-treated dogs versus 2 of 14 controls (two-tailed Fisher's exact test: P = 1.00). GVHD was seen in 4 of 9 rhG-CSF-treated dogs compared with 1 of 12 controls (P = .12). Two G-CSF-treated dogs died of GVHD versus none of the controls (P = .17). No unusual toxicities were seen in dogs receiving rhG-CSF. In summary, rhG-CSF significantly accelerated recovery of neutrophils, monocytes, and lymphocytes after DLA-identical littermate marrow transplantation without altering platelet recovery. Graft failure was not seen more often than in controls, but there was a trend toward an increased incidence of GVHD." @default.
• W338184868 created "2016-06-24" @default.
• W338184868 creator A5006104596 @default.
• W338184868 creator A5032653990 @default.
• W338184868 creator A5036305494 @default.
• W338184868 creator A5053309280 @default.
• W338184868 creator A5056405520 @default.
• W338184868 creator A5078553813 @default.
• W338184868 creator A5085787488 @default.
• W338184868 creator A5088481479 @default.
• W338184868 date "1990-08-01" @default.
• W338184868 modified "2023-10-06" @default.
• W338184868 title "Recombinant human granulocyte colony-stimulating factor accelerates hematopoietic recovery after DLA-identical littermate marrow transplants in dogs" @default.
• W338184868 cites W1515515119 @default.
• W338184868 cites W1979300931 @default.
• W338184868 cites W1987951694 @default.
• W338184868 cites W2025637191 @default.
• W338184868 cites W2050149613 @default.
• W338184868 cites W2052907764 @default.
• W338184868 cites W2089222319 @default.
• W338184868 cites W2092368843 @default.
• W338184868 cites W2150290224 @default.
• W338184868 cites W2265066695 @default.
• W338184868 cites W2337969406 @default.
• W338184868 cites W2345369541 @default.
• W338184868 cites W2402094753 @default.
• W338184868 cites W2421429518 @default.
• W338184868 cites W2462754346 @default.
• W338184868 cites W2764379217 @default.
• W338184868 cites W95208818 @default.
• W338184868 doi "https://doi.org/10.1182/blood.v76.3.636.636" @default.
• W338184868 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1696148" @default.
• W338184868 hasPublicationYear "1990" @default.
• W338184868 type Work @default.
• W338184868 sameAs 338184868 @default.
• W338184868 citedByCount "14" @default.
• W338184868 crossrefType "journal-article" @default.
• W338184868 hasAuthorship W338184868A5006104596 @default.
• W338184868 hasAuthorship W338184868A5032653990 @default.
• W338184868 hasAuthorship W338184868A5036305494 @default.
• W338184868 hasAuthorship W338184868A5053309280 @default.
• W338184868 hasAuthorship W338184868A5056405520 @default.
• W338184868 hasAuthorship W338184868A5078553813 @default.
• W338184868 hasAuthorship W338184868A5085787488 @default.
• W338184868 hasAuthorship W338184868A5088481479 @default.
• W338184868 hasBestOaLocation W3381848681 @default.
• W338184868 hasConcept C109159458 @default.
• W338184868 hasConcept C120665830 @default.
• W338184868 hasConcept C121332964 @default.
• W338184868 hasConcept C126322002 @default.
• W338184868 hasConcept C141071460 @default.
• W338184868 hasConcept C2776694085 @default.
• W338184868 hasConcept C2776755627 @default.
• W338184868 hasConcept C2777767877 @default.
• W338184868 hasConcept C2777983669 @default.
• W338184868 hasConcept C2778880498 @default.
• W338184868 hasConcept C2780007613 @default.
• W338184868 hasConcept C28328180 @default.
• W338184868 hasConcept C2911091166 @default.
• W338184868 hasConcept C54355233 @default.
• W338184868 hasConcept C61511704 @default.
• W338184868 hasConcept C71924100 @default.
• W338184868 hasConcept C86803240 @default.
• W338184868 hasConcept C88879693 @default.
• W338184868 hasConcept C89560881 @default.
• W338184868 hasConcept C90924648 @default.
• W338184868 hasConceptScore W338184868C109159458 @default.
• W338184868 hasConceptScore W338184868C120665830 @default.
• W338184868 hasConceptScore W338184868C121332964 @default.
• W338184868 hasConceptScore W338184868C126322002 @default.
• W338184868 hasConceptScore W338184868C141071460 @default.
• W338184868 hasConceptScore W338184868C2776694085 @default.
• W338184868 hasConceptScore W338184868C2776755627 @default.
• W338184868 hasConceptScore W338184868C2777767877 @default.
• W338184868 hasConceptScore W338184868C2777983669 @default.
• W338184868 hasConceptScore W338184868C2778880498 @default.
• W338184868 hasConceptScore W338184868C2780007613 @default.
• W338184868 hasConceptScore W338184868C28328180 @default.
• W338184868 hasConceptScore W338184868C2911091166 @default.
• W338184868 hasConceptScore W338184868C54355233 @default.
• W338184868 hasConceptScore W338184868C61511704 @default.
• W338184868 hasConceptScore W338184868C71924100 @default.
• W338184868 hasConceptScore W338184868C86803240 @default.
• W338184868 hasConceptScore W338184868C88879693 @default.
• W338184868 hasConceptScore W338184868C89560881 @default.
• W338184868 hasConceptScore W338184868C90924648 @default.
• W338184868 hasLocation W3381848681 @default.
• W338184868 hasOpenAccess W338184868 @default.
• W338184868 hasPrimaryLocation W3381848681 @default.
• W338184868 hasRelatedWork W1421046027 @default.
• W338184868 hasRelatedWork W160332237 @default.
• W338184868 hasRelatedWork W191242793 @default.
• W338184868 hasRelatedWork W1973312385 @default.
• W338184868 hasRelatedWork W2017416417 @default.
• W338184868 hasRelatedWork W2025110885 @default.
• W338184868 hasRelatedWork W2027137333 @default.
• W338184868 hasRelatedWork W2050149613 @default.
• W338184868 hasRelatedWork W2071831066 @default.
• W338184868 hasRelatedWork W2092368843 @default.
• W338184868 hasRelatedWork W2135729119 @default.

• next