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- W340053413 abstract "Objective To observe the eradication rate and side-effect of probiotics supplementation on anti-Helicobacter pylori triple therapy.Methods The 200 patients with peptic ulcer or chronic gastritis,in whom the results were both positive for the 14C-urea breath test and the rapid urease test,were divided into two groups randomly,i.e,group A was assigned to 14d triple therapy consisting of esomeprazole,clarithromycin and amoxicillin,group B was assigned to 14d triple therapy plus Medilac-S(Bacillus subtilis,Streptococcus faecium).The side-effects questionnaire was filled in once a week.The effect on eradication of Helicobacter pylori was determined by the 14C-urea breath test and the rapid urease test again four weeks later after finishing cure.Results The eradication rate of both groups was approximate,92.30% and 93.88%,respectively(P0.05).The gastrointestinal side-effects were obviously fewer in group B than that in group A(P0.01).Conclution Medilac-S supplementation may cut down gastrointestinal side-effects related to anti-Helicobacter pylori triple therapy,and shows a significant improvement in treatment tolerability." @default.
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- W340053413 date "2009-01-01" @default.
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- W340053413 title "Impact of probiotics on anti-Helicobacter pylori therapy." @default.
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