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• W340904510 abstract "Abstract : The DoD is responsible for the management of thousands of sites with organic compounds and metals contamination in soils and sediments. The current regulatory paradigm for characterizing risks associated with the level of contamination in soils and sediments generally does not include measures of the actual bioavailability of these contaminants to human or ecological receptors. However, there is clear and growing evidence that demonstrates that some of these contaminants are less available to potentially harm humans or ecological receptors than is suggested by simply extrapolating effects based on total concentrations of contaminants in bulk soil or sediment. As a result, bulk soil or sediment concentrations frequently overestimate actual risks and cleanup levels based on such concentrations may be overprotective. Physical and chemical sequestration processes can reduce the potential for exposure and/or uptake by living organisms, but these changes in bioaccessibility and bioavailability are generally not addressed when setting riskbased cleanup criteria. Explicitly assessing contaminant bioavailability can result in setting more technically defensible cleanup goals and establishing more realistic cleanup priorities, while still ensuring protection of human health and the environment. Although the science supports incorporating site-specific bioavailability measurements into risk assessments and site management decisions, the current regulatory paradigm does not make this mandatory. This should change. Additionally, methods for assessing and reducing contaminant bioavailability should continue to be refined and validated. The workshop described in this document was convened by SERDP and ESTCP on August 20- 21, 2008, in Annapolis, MD, to determine future research and demonstration needs in the area of bioavailability and its use in the risk-based remedial decision-making process at DoD sites." @default.
• W340904510 created "2016-06-24" @default.
• W340904510 creator A5001814782 @default.
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• W340904510 date "2008-11-01" @default.
• W340904510 modified "2023-09-27" @default.
• W340904510 title "SERDP and ESTCP Expert Panel Workshop on Research and Development Needs for Understanding and Assessing the Bioavailability of Contaminants in Soils and Sediments" @default.
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