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• W3409586 abstract "Research Article1 September 1983free access Two specific markers for neural differentiation of embryonal carcinoma cells. B. Eddé B. Eddé Service de Génétique cellulaire du Collège de France et de l'Institut Pasteur, Paris. Search for more papers by this author H. Jakob H. Jakob Service de Génétique cellulaire du Collège de France et de l'Institut Pasteur, Paris. Search for more papers by this author M. Darmon M. Darmon Service de Génétique cellulaire du Collège de France et de l'Institut Pasteur, Paris. Search for more papers by this author B. Eddé B. Eddé Service de Génétique cellulaire du Collège de France et de l'Institut Pasteur, Paris. Search for more papers by this author H. Jakob H. Jakob Service de Génétique cellulaire du Collège de France et de l'Institut Pasteur, Paris. Search for more papers by this author M. Darmon M. Darmon Service de Génétique cellulaire du Collège de France et de l'Institut Pasteur, Paris. Search for more papers by this author Author Information B. Eddé1, H. Jakob1 and M. Darmon1 1Service de Génétique cellulaire du Collège de France et de l'Institut Pasteur, Paris. The EMBO Journal (1983)2:1473-1478https://doi.org/10.1002/j.1460-2075.1983.tb01610.x PDFDownload PDF of article text and main figures. ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InMendeleyWechatReddit Figures & Info Two multipotential embryonal carcinoma (EC) cell lines, 1003 and 1009, can be induced to form preferentially neural derivatives in vitro. Synthesis of specific proteins during neural differentiation was followed by two-dimensional gel electrophoresis. The comparison of protein patterns obtained with neural and non-neural derivatives of these EC cell lines indicates that two changes are specific for the neural pathway: (i) the appearance of a new beta-tubulin isoform and (ii) the accumulation of the brain isozyme of creatine phosphokinase already present in small amounts in EC stem cells. These changes were found to take place early in the course of differentiation and to occur even when neurite outgrowth was prevented. Previous ArticleNext Article Volume 2Issue 91 September 1983In this issue RelatedDetailsLoading ..." @default.
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• W3409586 title "Two specific markers for neural differentiation of embryonal carcinoma cells." @default.
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