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- W342302015 abstract "The demonstration of a defect in insulin-mediated glucose metabolism in essential hypertension has raised the interest of both the “metabolists,” who have gained new insight into the pathogenesis of insulin resistance, and the “hypertensionologists,” who have focused attention on the cardiovascular actions of insulin. Although the metabolic consequences of insulin resistance are well established, there are differing views regarding the pathogenesis of the defect and its impact on blood pressure (BP) homeostasis. Whether high BP and insulin resistance have a common genetic basis, or whether they share common pathogenetic links (in this case, whether one affects the other or both stem from a common abnormality) is still debated. These possibilities are under active investigation, and although a comprehensive explanation for the observed association is not yet available, the effort has rapidly led to the accumulation of physiologically relevant information. In the present chapter, we shall try to separate facts from opinions with full cognizance that this scope will not be entirely met. Particularly with a complex issue, some degree of bias is inevitable." @default.
- W342302015 created "2016-06-24" @default.
- W342302015 creator A5027821454 @default.
- W342302015 creator A5055458112 @default.
- W342302015 creator A5089847244 @default.
- W342302015 date "1997-01-01" @default.
- W342302015 modified "2023-09-26" @default.
- W342302015 title "Hypertension and Insulin Resistance" @default.
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- W342302015 doi "https://doi.org/10.1007/978-1-4757-3906-0_16" @default.
- W342302015 hasPublicationYear "1997" @default.
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