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- W342629061 abstract "The stereospecific hydrolysis of mandelate can be effectively catalyzed by hyperthermophilic acylpeptide esterase APE 1547(Aeropyrum pernix esterase 1547). APE 1547 used in this reaction showed a remarkable stereodi-scrimination in favour of R-mandelic acid(99% e.e.) with an enantiomeric ratio E200. The results of computer simulation are consistent with the experimental results. It can be inferred that the R-substrate adopted a binding mode productive of the reaction due to the formation of the hydrogen bond at the active site of APE 1547." @default.
- W342629061 created "2016-06-24" @default.
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- W342629061 date "2011-01-01" @default.
- W342629061 modified "2023-09-23" @default.
- W342629061 title "Molecular Basis for Stereospecific Hydrolysis of Ethyl Mandelate by Thermophilic Esterase" @default.
- W342629061 hasPublicationYear "2011" @default.
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