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- W343169103 abstract "Many kidney disease processes begin with changes in the microscopic tissue structure, particularly the vasculature. Ultrasonic analysis can detect the changes [8, 6] that lead to earlier treatment and improved patient outcome. To characterize the microstructure, we estimate the average size of tissue scatterers D by analyzing the change in the backscatter coefficient σ(u) versus frequency u. The expression σ(u) = σ0 (u)Γ(u,D) summarizes the measurement technique, assuming the tissue structure is random [7]. An acoustic form factor is estimated from the echo spectrum using ( hat Gamma (u,D) = sigma (u)/sigma _0 (u) ). This estimate is compared to model functions Γ(u, D) for a range of D values. The model function that produces the smallest mean-square error when compared to the estimate ( hat Gamma ) determines the scatterer size estimate. Form factors provide a link between measurement and theory that may be used to estimate scatterer sizes for random media in the range of 25 µm to 400µm using diagnostic frequencies between 1 and 15 MHz." @default.
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- W343169103 date "1996-01-01" @default.
- W343169103 modified "2023-09-27" @default.
- W343169103 title "Renal Function Assessed by Monitoring the Size of Acoustic Scatterers: Map Estimators and the Use of Prior Information" @default.
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- W343169103 doi "https://doi.org/10.1007/978-1-4419-8772-3_28" @default.
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