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- W34358654 abstract "The first description of brain arteriovenous malformations (AVMs) can be found in the observations of Luschka1 and Virchow2 in the mid 19th century: they were generally categorized as vascular hamartomas. It is believed that the majority of these lesions are congenital in origin, arising between three and eight weeks of gestation3-5. Morphologically, they resemble the normal anastomotic plexuses formed during the early embryogenesis of the brain vascular system. Several recent studies have revealed possible factors involved in the formation and pathogenesis of AVMs. In particular, the gene that results in the production of endothelin-1, the potent vasoconstrictor agent involved in vascular cell growth, has been found to be repressed in cerebral AVMs; this may be the possible cause of the abnormal autoregulation found in AVMs6." @default.
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- W34358654 date "2008-03-01" @default.
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- W34358654 title "Operative Classification of Brain Arteriovenous Malformations" @default.
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- W34358654 doi "https://doi.org/10.1177/159101990801400102" @default.
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