FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W343726920> ?p ?o ?g. }

• W343726920 abstract "Carcinogenesis is a multistage process involving both genetic and epigenetic aberrations. Activation of proto-oncogenes and/or inactivation of tumor suppressor genes may occur in an early stage of carcinogenesis, i.e., tumor initiation, as well as in the later stages e.g., tumor conversion and progression (Fig. 1). For example, activation of Ki-ras by base substitution mutations is an early event in human colon carcinogenesis (Vogelstein et al., 1988), whereas amplification of N-myc is associated with the tumor progression stage of human neuroblastoma (Brodeur et al., 1987). In the inherited form of retinoblastoma, a defective tumor suppressor gene, Rb-1, is found in the germline DNA and the second Rb-1 allele is inactivated most frequently by deletion or recombinational mechanisms during the initia1 stages of carcinogenesis (Knudson, 1985; Hansen et al., 1985; Cavenee et al., 1986; Friend et al., 1986; Fung et al., 1987). In contrast, the inactivation by somatic mutation of both alleles of the p53 gene appears to occur during tumor progression of human carcinomas of the colon (Baker et al., 1989), breast and lung (Nigro et al., 1989)." @default.
• W343726920 created "2016-06-24" @default.
• W343726920 creator A5000601994 @default.
• W343726920 creator A5002231077 @default.
• W343726920 creator A5022046476 @default.
• W343726920 creator A5029647070 @default.
• W343726920 creator A5050126669 @default.
• W343726920 creator A5064366381 @default.
• W343726920 creator A5071719987 @default.
• W343726920 creator A5077253237 @default.
• W343726920 creator A5082237312 @default.
• W343726920 date "1990-01-01" @default.
• W343726920 modified "2023-09-26" @default.
• W343726920 title "Oncogenes and Tumor Suppressor Genes Involved in Human Lung Carcinogenesis" @default.
• W343726920 cites W101106793 @default.
• W343726920 cites W1804112400 @default.
• W343726920 cites W1913952795 @default.
• W343726920 cites W1971972605 @default.
• W343726920 cites W1974967257 @default.
• W343726920 cites W1980254549 @default.
• W343726920 cites W1982361487 @default.
• W343726920 cites W1987460795 @default.
• W343726920 cites W1988088718 @default.
• W343726920 cites W1989052124 @default.
• W343726920 cites W1989752636 @default.
• W343726920 cites W1992409084 @default.
• W343726920 cites W1992682395 @default.
• W343726920 cites W1993715195 @default.
• W343726920 cites W1998562271 @default.
• W343726920 cites W2000729741 @default.
• W343726920 cites W2012034467 @default.
• W343726920 cites W2019187279 @default.
• W343726920 cites W2020593103 @default.
• W343726920 cites W2025615787 @default.
• W343726920 cites W2026070941 @default.
• W343726920 cites W2029014948 @default.
• W343726920 cites W2032631136 @default.
• W343726920 cites W2034440981 @default.
• W343726920 cites W2035975217 @default.
• W343726920 cites W2037312854 @default.
• W343726920 cites W2040834490 @default.
• W343726920 cites W2040954918 @default.
• W343726920 cites W2041150657 @default.
• W343726920 cites W2045423010 @default.
• W343726920 cites W2052878543 @default.
• W343726920 cites W2053501297 @default.
• W343726920 cites W2054549064 @default.
• W343726920 cites W2058392986 @default.
• W343726920 cites W2069100534 @default.
• W343726920 cites W2073683003 @default.
• W343726920 cites W2075300416 @default.
• W343726920 cites W2080016765 @default.
• W343726920 cites W2081969062 @default.
• W343726920 cites W2085226130 @default.
• W343726920 cites W2085679251 @default.
• W343726920 cites W2091723114 @default.
• W343726920 cites W2093517913 @default.
• W343726920 cites W2099742439 @default.
• W343726920 cites W2113207529 @default.
• W343726920 cites W2120840803 @default.
• W343726920 cites W2140566800 @default.
• W343726920 cites W2146529796 @default.
• W343726920 cites W2154109712 @default.
• W343726920 cites W2166208988 @default.
• W343726920 cites W2167202601 @default.
• W343726920 cites W2170844556 @default.
• W343726920 cites W2315734235 @default.
• W343726920 cites W2318463652 @default.
• W343726920 cites W2320138981 @default.
• W343726920 cites W2337563725 @default.
• W343726920 cites W2412672267 @default.
• W343726920 cites W98587092 @default.
• W343726920 doi "https://doi.org/10.1007/978-1-4613-0637-5_29" @default.
• W343726920 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2282044" @default.
• W343726920 hasPublicationYear "1990" @default.
• W343726920 type Work @default.
• W343726920 sameAs 343726920 @default.
• W343726920 citedByCount "4" @default.
• W343726920 crossrefType "book-chapter" @default.
• W343726920 hasAuthorship W343726920A5000601994 @default.
• W343726920 hasAuthorship W343726920A5002231077 @default.
• W343726920 hasAuthorship W343726920A5022046476 @default.
• W343726920 hasAuthorship W343726920A5029647070 @default.
• W343726920 hasAuthorship W343726920A5050126669 @default.
• W343726920 hasAuthorship W343726920A5064366381 @default.
• W343726920 hasAuthorship W343726920A5071719987 @default.
• W343726920 hasAuthorship W343726920A5077253237 @default.
• W343726920 hasAuthorship W343726920A5082237312 @default.
• W343726920 hasConcept C104317684 @default.
• W343726920 hasConcept C13514818 @default.
• W343726920 hasConcept C143589142 @default.
• W343726920 hasConcept C153911025 @default.
• W343726920 hasConcept C179185449 @default.
• W343726920 hasConcept C180754005 @default.
• W343726920 hasConcept C2776577112 @default.
• W343726920 hasConcept C2778264664 @default.
• W343726920 hasConcept C2779256057 @default.
• W343726920 hasConcept C41091548 @default.
• W343726920 hasConcept C501734568 @default.
• W343726920 hasConcept C502942594 @default.

• next