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- W34457175 endingPage "394" @default.
- W34457175 startingPage "367" @default.
- W34457175 abstract "The processes of drug absorption, distribution, metabolism and excretion, and the rates at which they occur, are recognized as critical factors influencing the degree and time course of drug pharmacologic action in the body. Disease states affecting different organs may have a variety of effects on drug disposition and also on pharmacologic and pharmacodynamic effects. The two organs that are recognized as having the greatest influence on drug disposition, either directly or indirectly, are the kidney and the liver. While most clinical studies carried out early in drug development are conducted in healthy subjects. renal or hepatic impairment may exert a considerable influence on both the disposition and the pharmacodynamic consequences of an administered drug." @default.
- W34457175 created "2016-06-24" @default.
- W34457175 creator A5062397507 @default.
- W34457175 creator A5078248936 @default.
- W34457175 date "1996-01-01" @default.
- W34457175 modified "2023-10-12" @default.
- W34457175 title "Effect of Liver Disease on Drug Metabolism and Pharmacokinetics" @default.
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