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- W344959546 abstract "Human IgA1 myeloma proteins having antibody activity against staphylococcal α-toxin were found to inhibit complement activation mediated by human polyclonal or monoclonal antibodies against the same antigen. Fabα fragments of the IgA1 antibodies, obtained by cleavage with IgA1 protease from Haemophilus influenzae, possessed ability to inhibit complement activation similar to the intact IgA1 antibodies. Cleavage by IgA1 proteases may not only diminish the mucosal protective activity of secretory IgA1 antibodies, but in addition, the resulting Fabα antibody fragments may protect invasive bacteria against systemic immune defense mechanisms" @default.
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- W344959546 date "1989-01-01" @default.
- W344959546 modified "2023-10-18" @default.
- W344959546 title "Significance of Fab Fragments of IgA1 Antibodies in Bacterial Evasion of Host Defense Mechanisms" @default.
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- W344959546 doi "https://doi.org/10.1016/b978-0-08-037378-2.50032-2" @default.
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