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- W346087943 abstract "The transmission of infectious agents from domestic animals to humans is a matter of particular concern at present. Inoculation can enhance the defences of each individual animal but only in the short term. Certainly, it will be of immense benefit if biotechnology and genetic techniques are applied to farm animal breeding and selection programs to improve productivity, performance and health status as well as for the construction of sustainable animal production systems and promotion of animal welfare. In recent years, efforts to drive candidate genes like cytokines, haptoglobin, complement system, C-reactive protein, a 2-macroglobulin, retinol binding protein, transcortin, and etc. associated with immune traits have successfully been studied in human and different animal species. Here, we compared the molecular structure and evaluated the expression tendency of the haemolytic complement activity (HCA) of porcine candidate genes encoding the terminal complement components (TCC) C6-9. The results suggested that (1) high homology of complement genes among mammalian species may open new ways in cure/ treatment of disease; (2) Muong Khuong animals (Vietnamese potbelly pig) have a great genetic potential to improve the health status of pigs; and (3) HCA in the classical pathway can be developed further by different activation modes, with the potential improvement of animal health." @default.
- W346087943 created "2016-06-24" @default.
- W346087943 creator A5050419481 @default.
- W346087943 date "2013-01-31" @default.
- W346087943 modified "2023-10-18" @default.
- W346087943 title "Structural homology and expression tendency of the natural immune response of the terminal complement components to inoculations in pigs: a review" @default.
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- W346087943 doi "https://doi.org/10.17221/6650-vetmed" @default.
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