Matches in SemOpenAlex for { <https://semopenalex.org/work/W34784622> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W34784622 endingPage "343" @default.
- W34784622 startingPage "336" @default.
- W34784622 abstract "Lung-washings from mammalian species are a rich source of surfactant and of cells, predominantly alveolar macrophages, that could be important in the metabolism of the surfactant. We obtained washings from normal dogs, and from dogs that had had one pulmonary artery (PA) ligated 1 or 2 days earlier. Centrifugation of wash (400 × g for 20 min) separated a sediment, made up of cells at the bottom and a white layer, largely acellular, from the supernatant. The volume of sediment averaged 2.1 ± 1.4 ml,. 75% of which was white layer. The cells resembled the large alveolar (type II) cells found in the lung; however they differed by at least one major histochemical reaction. The white layer had greater surface activity than the cells or the supernate, and was richest in phospholipids and lecithin. The cells lost their surface activity when rinsed and resuspended. These observations suggest that surfactant is normally present, mainly in an acellular fraction and possibly at the surface of the alveolar cells. The alveolar macrophages may either store surfactant, rather than synthesize it, or simply acquire a coat of surfactant during sedimentation. After PA ligation, the earliest abnormality was a decrease in the white layer; the cells were fewer, smaller, and weaker in metabolic activity." @default.
- W34784622 created "2016-06-24" @default.
- W34784622 creator A5046188490 @default.
- W34784622 creator A5072028861 @default.
- W34784622 creator A5072457191 @default.
- W34784622 creator A5078381271 @default.
- W34784622 date "1968-02-01" @default.
- W34784622 modified "2023-10-16" @default.
- W34784622 title "Surface tension, metabolic activity, and lipid composition of alveolar cells in washings from normal dog lungs and after pulmonary artery ligation" @default.
- W34784622 cites W14432163 @default.
- W34784622 cites W1513741126 @default.
- W34784622 cites W1515575932 @default.
- W34784622 cites W1605762065 @default.
- W34784622 cites W2016209835 @default.
- W34784622 cites W2021052427 @default.
- W34784622 cites W2081059755 @default.
- W34784622 cites W2098856298 @default.
- W34784622 cites W2135392920 @default.
- W34784622 cites W2168526937 @default.
- W34784622 cites W2176220646 @default.
- W34784622 cites W2254187400 @default.
- W34784622 cites W2287372437 @default.
- W34784622 cites W2346801008 @default.
- W34784622 cites W2347130361 @default.
- W34784622 cites W2398216710 @default.
- W34784622 cites W2399624914 @default.
- W34784622 cites W2421952466 @default.
- W34784622 cites W261416222 @default.
- W34784622 cites W310756386 @default.
- W34784622 cites W934627980 @default.
- W34784622 doi "https://doi.org/10.1172/jci105729" @default.
- W34784622 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/297175" @default.
- W34784622 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12066777" @default.
- W34784622 hasPublicationYear "1968" @default.
- W34784622 type Work @default.
- W34784622 sameAs 34784622 @default.
- W34784622 citedByCount "32" @default.
- W34784622 crossrefType "journal-article" @default.
- W34784622 hasAuthorship W34784622A5046188490 @default.
- W34784622 hasAuthorship W34784622A5072028861 @default.
- W34784622 hasAuthorship W34784622A5072457191 @default.
- W34784622 hasAuthorship W34784622A5078381271 @default.
- W34784622 hasBestOaLocation W347846221 @default.
- W34784622 hasConcept C126322002 @default.
- W34784622 hasConcept C142724271 @default.
- W34784622 hasConcept C153911025 @default.
- W34784622 hasConcept C179437574 @default.
- W34784622 hasConcept C185592680 @default.
- W34784622 hasConcept C2777714996 @default.
- W34784622 hasConcept C2779564620 @default.
- W34784622 hasConcept C55493867 @default.
- W34784622 hasConcept C58226133 @default.
- W34784622 hasConcept C71924100 @default.
- W34784622 hasConcept C7623868 @default.
- W34784622 hasConcept C86803240 @default.
- W34784622 hasConceptScore W34784622C126322002 @default.
- W34784622 hasConceptScore W34784622C142724271 @default.
- W34784622 hasConceptScore W34784622C153911025 @default.
- W34784622 hasConceptScore W34784622C179437574 @default.
- W34784622 hasConceptScore W34784622C185592680 @default.
- W34784622 hasConceptScore W34784622C2777714996 @default.
- W34784622 hasConceptScore W34784622C2779564620 @default.
- W34784622 hasConceptScore W34784622C55493867 @default.
- W34784622 hasConceptScore W34784622C58226133 @default.
- W34784622 hasConceptScore W34784622C71924100 @default.
- W34784622 hasConceptScore W34784622C7623868 @default.
- W34784622 hasConceptScore W34784622C86803240 @default.
- W34784622 hasIssue "2" @default.
- W34784622 hasLocation W347846221 @default.
- W34784622 hasLocation W347846222 @default.
- W34784622 hasLocation W347846223 @default.
- W34784622 hasLocation W347846224 @default.
- W34784622 hasOpenAccess W34784622 @default.
- W34784622 hasPrimaryLocation W347846221 @default.
- W34784622 hasRelatedWork W1977664181 @default.
- W34784622 hasRelatedWork W2007420540 @default.
- W34784622 hasRelatedWork W2021811586 @default.
- W34784622 hasRelatedWork W2034654197 @default.
- W34784622 hasRelatedWork W2041875759 @default.
- W34784622 hasRelatedWork W2044784388 @default.
- W34784622 hasRelatedWork W2046674828 @default.
- W34784622 hasRelatedWork W2088950583 @default.
- W34784622 hasRelatedWork W2306890945 @default.
- W34784622 hasRelatedWork W282551611 @default.
- W34784622 hasVolume "47" @default.
- W34784622 isParatext "false" @default.
- W34784622 isRetracted "false" @default.
- W34784622 magId "34784622" @default.
- W34784622 workType "article" @default.