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- W348565867 abstract "A reply is offered to an article likening the use of condoms to Russian roulette in its vaunted protection against AIDS. The Food and Drug Administration endorsed the use of nonoxynol-9 in condoms against infection with the human immunodeficiency virus (HIV) and genital herpes. 1985 research indicated that nonoxynol-9 inactivated HIV in vitro in concentrations below 0.05%. At a 1987 congress on AIDS a study was presented involving the testing of 30 condoms. 20 contained 0.9 ml of 6.6% nonoxynol-9 and 10 contained none of the substance. Each condom was placed on an empty sterilized contraception in a glass cylinder containing a 10 ml substrate of flowing synthetic tissue culture (RPMJ 1640), and 4 ml of HIV inoculum was put on top of the condoms. Anal or vaginal intercourse was simulated for 5 minutes. After each simulation 1 ml of the test material of the test material was taken out of the cylinder and from the top of the condom for HIV testing. 10 condoms without nonoxynol-9 were all HIV negative, where the test sample was taken from the outside and inside of condoms after the first simulated intercourse but before a hole was pierced into the condoms. None of the test samples taken from the inside of the condoms were HIV positive among 10 other condoms containing nonoxynol-9 with HIV inoculum. 2 of these 10 sample test taken from the outside before a hole was pierced proved to be positive among 10 condoms containing nonoxynol-9 with HIV inoculum on the outside. HIV could not be detected on the outside of any of the 20 condoms containing nonoxynol-9, even after rupture. Intact latex condoms are impervious to HIV, and those with nonoxynol-9 inactivate it in concentrations above 0.25%, even if the condom breaks." @default.
- W348565867 created "2016-06-24" @default.
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- W348565867 date "1991-01-23" @default.
- W348565867 modified "2023-09-25" @default.
- W348565867 title "[Nonoxynol-9 in a perforated condom protects against HIV infection]." @default.
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