FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W350005650> ?p ?o ?g. }

• W350005650 endingPage "415" @default.
• W350005650 startingPage "410" @default.
• W350005650 abstract "Allogeneic bone marrow transplantation (BMT) is the only curative therapy for chronic myelogenous leukemia (CML), though several studies indicate that prolonged survival can result from interferon- (IFN-) treatment. IFN- is now often used as initial therapy for CML, before donor availability is known. Because identifying potential donors can take several weeks to months, it is important to know whether IFN- adversely affects outcome of a subsequent BMT. If it does, initiation of IFN- therapy might be delayed until donor availability is determined and avoided in patients for whom BMT is planned. We studied 873 patients who received HLA-identical sibling BMT for chronic-phase CML in 153 centers participating in the International Bone Marrow Transplant Registry. The object was to compare outcome in the 664 who received only hydroxyurea before BMT with outcome in the 209 who received IFN- with or without hydroxyurea. The median duration of IFN- therapy was 2 months (range, 1 to 39 months). Cox proportional hazards analysis was used to compare engraftment, graft-versus-host disease (GVHD), nonrelapse mortality, relapse, survival, and leukemia-free survival after adjustment for other prognostic variables. We found a higher risk of nonengraftment among patients given IFN- than among those given hydroxyurea alone (2% versus 0.2%; P  = 0.01). Patients who received IFN- had a lower risk of relapse (relative risk, 0.17; 95% confidence interval, 0.04-0.70). Probabilities of GVHD, nonrelapse mortality, survival, and leukemia-free survival were similar in the two treatment groups. These results suggest that a short course of IFN- does not adversely affect survival after a subsequent HLA-identical sibling BMT for chronic-phase CML." @default.
• W350005650 created "2016-06-24" @default.
• W350005650 creator A5003621767 @default.
• W350005650 creator A5006812700 @default.
• W350005650 creator A5020401806 @default.
• W350005650 creator A5020916914 @default.
• W350005650 creator A5029953583 @default.
• W350005650 creator A5037299848 @default.
• W350005650 creator A5039305143 @default.
• W350005650 creator A5050851527 @default.
• W350005650 creator A5070096873 @default.
• W350005650 creator A5071051461 @default.
• W350005650 creator A5088486180 @default.
• W350005650 creator A5091433944 @default.
• W350005650 date "2000-01-15" @default.
• W350005650 modified "2023-10-10" @default.
• W350005650 title "Effect of short-term interferon therapy on the outcome of subsequent HLA-identical sibling bone marrow transplantation for chronic myelogenous leukemia: an analysis from the International Bone Marrow Transplant Registry" @default.
• W350005650 cites W1498708301 @default.
• W350005650 cites W1504310442 @default.
• W350005650 cites W1551203462 @default.
• W350005650 cites W188630774 @default.
• W350005650 cites W1893871329 @default.
• W350005650 cites W1928548710 @default.
• W350005650 cites W1981066689 @default.
• W350005650 cites W2045789194 @default.
• W350005650 cites W2050642909 @default.
• W350005650 cites W2052071946 @default.
• W350005650 cites W2058190985 @default.
• W350005650 cites W2086602173 @default.
• W350005650 cites W2089697181 @default.
• W350005650 cites W2089998734 @default.
• W350005650 cites W2122455557 @default.
• W350005650 cites W2140134889 @default.
• W350005650 cites W2160842550 @default.
• W350005650 cites W2290614159 @default.
• W350005650 cites W2292226371 @default.
• W350005650 cites W2337277825 @default.
• W350005650 cites W2337803710 @default.
• W350005650 cites W2341783390 @default.
• W350005650 cites W2403285790 @default.
• W350005650 cites W2466763541 @default.
• W350005650 cites W2508058084 @default.
• W350005650 cites W2510493851 @default.
• W350005650 cites W2512753555 @default.
• W350005650 cites W3202813470 @default.
• W350005650 cites W38386901 @default.
• W350005650 cites W60081501 @default.
• W350005650 doi "https://doi.org/10.1182/blood.v95.2.410" @default.
• W350005650 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10627443" @default.
• W350005650 hasPublicationYear "2000" @default.
• W350005650 type Work @default.
• W350005650 sameAs 350005650 @default.
• W350005650 citedByCount "9" @default.
• W350005650 crossrefType "journal-article" @default.
• W350005650 hasAuthorship W350005650A5003621767 @default.
• W350005650 hasAuthorship W350005650A5006812700 @default.
• W350005650 hasAuthorship W350005650A5020401806 @default.
• W350005650 hasAuthorship W350005650A5020916914 @default.
• W350005650 hasAuthorship W350005650A5029953583 @default.
• W350005650 hasAuthorship W350005650A5037299848 @default.
• W350005650 hasAuthorship W350005650A5039305143 @default.
• W350005650 hasAuthorship W350005650A5050851527 @default.
• W350005650 hasAuthorship W350005650A5070096873 @default.
• W350005650 hasAuthorship W350005650A5071051461 @default.
• W350005650 hasAuthorship W350005650A5088486180 @default.
• W350005650 hasAuthorship W350005650A5091433944 @default.
• W350005650 hasConcept C126322002 @default.
• W350005650 hasConcept C138496976 @default.
• W350005650 hasConcept C141071460 @default.
• W350005650 hasConcept C143998085 @default.
• W350005650 hasConcept C15744967 @default.
• W350005650 hasConcept C203014093 @default.
• W350005650 hasConcept C2776194465 @default.
• W350005650 hasConcept C2776960273 @default.
• W350005650 hasConcept C2778461978 @default.
• W350005650 hasConcept C2780007613 @default.
• W350005650 hasConcept C2911091166 @default.
• W350005650 hasConcept C71924100 @default.
• W350005650 hasConceptScore W350005650C126322002 @default.
• W350005650 hasConceptScore W350005650C138496976 @default.
• W350005650 hasConceptScore W350005650C141071460 @default.
• W350005650 hasConceptScore W350005650C143998085 @default.
• W350005650 hasConceptScore W350005650C15744967 @default.
• W350005650 hasConceptScore W350005650C203014093 @default.
• W350005650 hasConceptScore W350005650C2776194465 @default.
• W350005650 hasConceptScore W350005650C2776960273 @default.
• W350005650 hasConceptScore W350005650C2778461978 @default.
• W350005650 hasConceptScore W350005650C2780007613 @default.
• W350005650 hasConceptScore W350005650C2911091166 @default.
• W350005650 hasConceptScore W350005650C71924100 @default.
• W350005650 hasIssue "2" @default.
• W350005650 hasLocation W3500056501 @default.
• W350005650 hasOpenAccess W350005650 @default.
• W350005650 hasPrimaryLocation W3500056501 @default.
• W350005650 hasRelatedWork W1430390330 @default.
• W350005650 hasRelatedWork W1511009642 @default.
• W350005650 hasRelatedWork W1707184873 @default.
• W350005650 hasRelatedWork W1799579309 @default.

• next