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- W350098538 abstract "The purpose of this research was to know the effect of experimental infection with a stock of Trypanosoma vivax from Zulia state, Venezuela, on haematological parameters in sheep. Eight cross-breed West-African sheep between 6 months and 1 year old were aleatory divided in two groups. The experimental group (four sheep) was inoculated intravenously with 2 mL of fresh blood contained 1.3 × 10 6 Tryp/mL from a positive ewe. The remaining four animals served as controls. The effects of the parasite on body temperature, parasitaemia, haematocrit, haemoglobin, leukocytes and total serum proteins were evaluated for 90 days. All the infected animals were positive for the parasite from 2 days post-inoculation, developing undulating parasitaemia and severe anaemia which persisted until the termination of the experiment. The course of experimental infection with T. vivax showed two phases: Phase 1, observed between first four weeks the post-infection period, the infected sheep developed high levels of parasitaemia, and decrease (P < 0.005) in haematocrit and haemoglobin compared to control group. Total leukocyte counts fell on the first week post-infection and remained much lower than the control group throughout the observation period. The second phase was evident from fifth week postinfection; in this period, the infected animals showed levels of parasitaemia lower than the preceding phase, remittent fever, persistence low values the haematocrit and haemoglobin, as well as, significant increase (P < 0.05) of serum proteins. The changes in the haematological parameters and body temperature were related to appear the trypanosomes in the circulation and to the intensity of parasitaemia." @default.
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- W350098538 date "2005-01-01" @default.
- W350098538 modified "2023-09-27" @default.
- W350098538 title "EFECTO DE LA INFECCIÓN EXPERIMENTAL CON Trypanosoma vivax SOBRE PARÁMETROS HEMATOLÓGICOS EN OVINOS Effect of Experimental Trypanosoma vivax Infection on Hematological Parameters in Sheep" @default.
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