Matches in SemOpenAlex for { <https://semopenalex.org/work/W35145002> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W35145002 endingPage "662" @default.
- W35145002 startingPage "653" @default.
- W35145002 abstract "Isotope (tritiated thymidine, [3H]Tdr) incorporation into lymphocytes from two marmoset species, New World primates which are haemopoietic chimeras, was studied using peripheral blood lymphocyte (PBL) cultures incubated in vitro for 1–5 days with different concentrations of Concanavalin A (Con A), leucoagglutinin (LA), bacterial lipopolysaccharide (LPS) from gram-negative bacteria, rabbit anti-marmoset immunoglobulin (anti-Ig) serum, thymosin or irradiated histoincompatible (xenogeneic) lymphocytes. Only the plant lectins and xenogeneic lymphoid cells stimulated the uptake of [3H]Tdr. Lymphocyte enrichment experiments demonstrated that cells responsive to plant lectins and xenoantigens were primarily thymus-derived (T) lymphocytes. Bacterial endotoxin (LPS), however, enhanced the mitogenic response of PBL to Con A when LPS and plant lectin were added together at culture initiation. Thymosin caused either enhancement or suppression of the response to Con A depending on its time of addition relative to lectin stimulation. Addition of thymosin to lymphocyte cultures with Con A or 24 h later caused a decrease in isotope incorporation, while addition of thymosin 48 h later caused a 12–100% increase in [3H]Tdr uptake. Lymphocyte chimerism did not influence the mitogenic response since single-born, nonchimeric marmosets responded to plant lectins in a manner similar to marmosets with varying proportions of chimeric blood elements. Cytological analysis of stimulated lymphocytes from heterosexual marmosets revealed the percentage chimerism in the polyclonal mitogenic response and the clonal mixed lymphocyte reaction to be similar." @default.
- W35145002 created "2016-06-24" @default.
- W35145002 creator A5079005543 @default.
- W35145002 creator A5086460310 @default.
- W35145002 creator A5091161225 @default.
- W35145002 date "1977-11-01" @default.
- W35145002 modified "2023-10-18" @default.
- W35145002 title "Mitogenic response of marmoset lymphocytes: cytokinetics and identification of responsive cells." @default.
- W35145002 cites W100040270 @default.
- W35145002 cites W142955843 @default.
- W35145002 cites W1503047883 @default.
- W35145002 cites W1503287204 @default.
- W35145002 cites W1543303774 @default.
- W35145002 cites W1634967536 @default.
- W35145002 cites W1863774198 @default.
- W35145002 cites W1970298897 @default.
- W35145002 cites W1985884355 @default.
- W35145002 cites W1986290104 @default.
- W35145002 cites W1988508992 @default.
- W35145002 cites W2016187099 @default.
- W35145002 cites W2039476365 @default.
- W35145002 cites W2058027036 @default.
- W35145002 cites W2061954876 @default.
- W35145002 cites W2071053198 @default.
- W35145002 cites W2094425647 @default.
- W35145002 cites W2107036768 @default.
- W35145002 cites W2177819542 @default.
- W35145002 cites W2334559694 @default.
- W35145002 cites W2413017351 @default.
- W35145002 cites W2413879252 @default.
- W35145002 cites W2415145556 @default.
- W35145002 cites W2424987333 @default.
- W35145002 cites W87082738 @default.
- W35145002 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1445517" @default.
- W35145002 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/145405" @default.
- W35145002 hasPublicationYear "1977" @default.
- W35145002 type Work @default.
- W35145002 sameAs 35145002 @default.
- W35145002 citedByCount "5" @default.
- W35145002 crossrefType "journal-article" @default.
- W35145002 hasAuthorship W35145002A5079005543 @default.
- W35145002 hasAuthorship W35145002A5086460310 @default.
- W35145002 hasAuthorship W35145002A5091161225 @default.
- W35145002 hasConcept C151730666 @default.
- W35145002 hasConcept C153911025 @default.
- W35145002 hasConcept C159654299 @default.
- W35145002 hasConcept C19869320 @default.
- W35145002 hasConcept C202751555 @default.
- W35145002 hasConcept C203014093 @default.
- W35145002 hasConcept C2776451592 @default.
- W35145002 hasConcept C2776453536 @default.
- W35145002 hasConcept C2777108182 @default.
- W35145002 hasConcept C2777761686 @default.
- W35145002 hasConcept C2778754761 @default.
- W35145002 hasConcept C2780758401 @default.
- W35145002 hasConcept C55493867 @default.
- W35145002 hasConcept C86803240 @default.
- W35145002 hasConcept C956191 @default.
- W35145002 hasConceptScore W35145002C151730666 @default.
- W35145002 hasConceptScore W35145002C153911025 @default.
- W35145002 hasConceptScore W35145002C159654299 @default.
- W35145002 hasConceptScore W35145002C19869320 @default.
- W35145002 hasConceptScore W35145002C202751555 @default.
- W35145002 hasConceptScore W35145002C203014093 @default.
- W35145002 hasConceptScore W35145002C2776451592 @default.
- W35145002 hasConceptScore W35145002C2776453536 @default.
- W35145002 hasConceptScore W35145002C2777108182 @default.
- W35145002 hasConceptScore W35145002C2777761686 @default.
- W35145002 hasConceptScore W35145002C2778754761 @default.
- W35145002 hasConceptScore W35145002C2780758401 @default.
- W35145002 hasConceptScore W35145002C55493867 @default.
- W35145002 hasConceptScore W35145002C86803240 @default.
- W35145002 hasConceptScore W35145002C956191 @default.
- W35145002 hasIssue "5" @default.
- W35145002 hasLocation W351450021 @default.
- W35145002 hasOpenAccess W35145002 @default.
- W35145002 hasPrimaryLocation W351450021 @default.
- W35145002 hasRelatedWork W1689720770 @default.
- W35145002 hasRelatedWork W2128548428 @default.
- W35145002 hasRelatedWork W2130206048 @default.
- W35145002 hasRelatedWork W2321768478 @default.
- W35145002 hasRelatedWork W2520779216 @default.
- W35145002 hasRelatedWork W2539517059 @default.
- W35145002 hasRelatedWork W2788566516 @default.
- W35145002 hasRelatedWork W3008240870 @default.
- W35145002 hasRelatedWork W3045915179 @default.
- W35145002 hasRelatedWork W4220929793 @default.
- W35145002 hasVolume "33" @default.
- W35145002 isParatext "false" @default.
- W35145002 isRetracted "false" @default.
- W35145002 magId "35145002" @default.
- W35145002 workType "article" @default.