Matches in SemOpenAlex for { <https://semopenalex.org/work/W35459968> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W35459968 endingPage "78" @default.
- W35459968 startingPage "67" @default.
- W35459968 abstract "A total of 201 Enterococcus faecalis strains isolated from different body sites were tested to (i) establish their antibiotic susceptibility pattern; (ii) determine the percentage of strains highly resistant (MIC greater than 2,000 micrograms/ml) to five aminoglycosides and (iii) know if the combination of penicillin or ampicillin plus an aminoglycoside is reliably synergistic for the strains with low-level resistance (MICs ranged from the break point of susceptibility for each aminoglycoside to 2,000 micrograms/ml). Erythromycin exhibited very poor activity with MIC90 greater than 128 micrograms/ml. Pefloxacin and norfloxacin had intermediate activity, inhibiting 50% of isolates at 4 micrograms/ml and 90% at 8 micrograms/ml. Trimethoprim-sulfamethoxazole (1:20) inhibited 94% of isolates at less than or equal to 2 micrograms/ml and 87.6% at less than or equal to 0.5 microgram/ml. Ampicillin, penicillin and piperacillin were the most potent agents studied. Ninety percent of strains were inhibited at 1 microgram/ml of ampicillin and 4 micrograms/ml of penicillin and piperacillin. The E. faecalis isolates were relatively or totally resistant to the aminoglycosides. Ninety six (47.8%) were highly resistant at least to one of them. High level resistance to streptomycin was found in 47.3% of all strains and was the most frequent resistance encountered; amikacin highly resistant strains were the less common and accounted for 4.5%. Low-level resistance to the aminoglycosides ranged from 50.2% (for streptomycin) to 94.5% (for amikacin). Thirty one E. faecalis isolates were selected for 24-time kill-assays. There was a good correlation between resistance to penicillin or ampicillin aminoglycoside synergy in all but 3 strains which were highly resistant. Among the strains with low-level resistance to the aminoglycosides, there was no synergy in 37 (63.8%) of 58 killing assays with each of the aminoglycosides combined with penicillin. These results demonstrate that the susceptibility to 2,000 micrograms/ml of the aminoglycoside does not assure the penicillin or ampicillin aminoglycoside synergism." @default.
- W35459968 created "2016-06-24" @default.
- W35459968 creator A5014688862 @default.
- W35459968 creator A5016142454 @default.
- W35459968 creator A5038534757 @default.
- W35459968 creator A5086131527 @default.
- W35459968 creator A5087927479 @default.
- W35459968 date "1991-04-01" @default.
- W35459968 modified "2023-09-23" @default.
- W35459968 title "Susceptibility of Enterococcus faecalis to twelve antibiotics, time-kill assays, and high-level aminoglycoside resistance in a university hospital in Argentina." @default.
- W35459968 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1815269" @default.
- W35459968 hasPublicationYear "1991" @default.
- W35459968 type Work @default.
- W35459968 sameAs 35459968 @default.
- W35459968 citedByCount "2" @default.
- W35459968 countsByYear W354599682016 @default.
- W35459968 crossrefType "journal-article" @default.
- W35459968 hasAuthorship W35459968A5014688862 @default.
- W35459968 hasAuthorship W35459968A5016142454 @default.
- W35459968 hasAuthorship W35459968A5038534757 @default.
- W35459968 hasAuthorship W35459968A5086131527 @default.
- W35459968 hasAuthorship W35459968A5087927479 @default.
- W35459968 hasConcept C174802600 @default.
- W35459968 hasConcept C185592680 @default.
- W35459968 hasConcept C2775832221 @default.
- W35459968 hasConcept C2775843808 @default.
- W35459968 hasConcept C2776021129 @default.
- W35459968 hasConcept C2777427914 @default.
- W35459968 hasConcept C2777637488 @default.
- W35459968 hasConcept C2777787772 @default.
- W35459968 hasConcept C2778193466 @default.
- W35459968 hasConcept C2778974779 @default.
- W35459968 hasConcept C2778977604 @default.
- W35459968 hasConcept C2779489039 @default.
- W35459968 hasConcept C2779895986 @default.
- W35459968 hasConcept C501593827 @default.
- W35459968 hasConcept C523546767 @default.
- W35459968 hasConcept C54355233 @default.
- W35459968 hasConcept C86803240 @default.
- W35459968 hasConcept C89423630 @default.
- W35459968 hasConceptScore W35459968C174802600 @default.
- W35459968 hasConceptScore W35459968C185592680 @default.
- W35459968 hasConceptScore W35459968C2775832221 @default.
- W35459968 hasConceptScore W35459968C2775843808 @default.
- W35459968 hasConceptScore W35459968C2776021129 @default.
- W35459968 hasConceptScore W35459968C2777427914 @default.
- W35459968 hasConceptScore W35459968C2777637488 @default.
- W35459968 hasConceptScore W35459968C2777787772 @default.
- W35459968 hasConceptScore W35459968C2778193466 @default.
- W35459968 hasConceptScore W35459968C2778974779 @default.
- W35459968 hasConceptScore W35459968C2778977604 @default.
- W35459968 hasConceptScore W35459968C2779489039 @default.
- W35459968 hasConceptScore W35459968C2779895986 @default.
- W35459968 hasConceptScore W35459968C501593827 @default.
- W35459968 hasConceptScore W35459968C523546767 @default.
- W35459968 hasConceptScore W35459968C54355233 @default.
- W35459968 hasConceptScore W35459968C86803240 @default.
- W35459968 hasConceptScore W35459968C89423630 @default.
- W35459968 hasIssue "2" @default.
- W35459968 hasLocation W354599681 @default.
- W35459968 hasOpenAccess W35459968 @default.
- W35459968 hasPrimaryLocation W354599681 @default.
- W35459968 hasRelatedWork W1940669354 @default.
- W35459968 hasRelatedWork W1975931596 @default.
- W35459968 hasRelatedWork W2033569039 @default.
- W35459968 hasRelatedWork W2090318531 @default.
- W35459968 hasRelatedWork W2113317018 @default.
- W35459968 hasRelatedWork W2123026163 @default.
- W35459968 hasRelatedWork W2411274360 @default.
- W35459968 hasRelatedWork W2412475263 @default.
- W35459968 hasRelatedWork W2417490474 @default.
- W35459968 hasRelatedWork W35459968 @default.
- W35459968 hasVolume "23" @default.
- W35459968 isParatext "false" @default.
- W35459968 isRetracted "false" @default.
- W35459968 magId "35459968" @default.
- W35459968 workType "article" @default.