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- W355305592 abstract "OBJECTIVE: This case series aims to characterize hypoglossal nerve palsy seen at the Mayo Clinic, initially with this series of Mayo Arizona patients, to be followed by a larger system-wide Mayo patient survey. BACKGROUND: Hypoglossal nerve palsy etiologies have generally fallen into the categories of vascular, radiation induced, or neoplastic per surveys conducted in the 1990s. No major surveys have been performed recently to look for new causes or distributions. DESIGN/METHODS: The Mayo Clinic Arizona database, spanning over a 27 year period, was searched for patients diagnosed as having hypoglossal nerve palsy. Of those consented and not diagnosed with ALS or trauma, 7 patients remained. RESULTS: Three patients were radiation induced, with one having CN V + XII involvement, a second having CN XI + XII involvement, and a third showing isolated disease of CN XII. All three had myokymia on tongue EMG. Vascular causes ranked second, with one patient developing CN XI + XII palsy from an internal carotid artery dissection and a second developing hypoglossal nerve palsy from medulla compression by an enlarged vertebral artery. One patient presented with a unique acute onset case attributable to a synovial cystic compression of the right hypoglossal canal coupled with congenitally narrowed hypoglossal canals in the setting of platybasia. Of note, no such case has been previously reported to our knowledge, including in a case series of 100 patients by Keane et al (1996). One case remained indeterminate with regards to etiology. CONCLUSIONS: Most patients presented either in the setting of a known cancer, prior external beam radiation or as chronic headache with imaging diagnostic of vascular etiologies. This study explores unique causes of hypoglossal nerve palsy, but also highlights an etiology not previously described, all of which should be entertained once more commonly held diagnostic considerations are excluded. Disclosure: Dr. Stino has nothing to disclose. Dr. Smith has received personal compensation in an editorial capacity for Elsevier." @default.
- W355305592 created "2016-06-24" @default.
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- W355305592 date "2015-04-06" @default.
- W355305592 modified "2023-09-24" @default.
- W355305592 title "Hypoglossal Nerve Palsy is Associated with a Variety of Etiologies and Sometimes Results in Tongue Myokymia (P7.049)" @default.
- W355305592 hasPublicationYear "2015" @default.
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