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- W35537551 endingPage "66" @default.
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- W35537551 abstract "G protein-coupled receptors (GPCRs) represent 50-60% of the current drug targets. There is no doubt that this family of membrane proteins plays a crucial role in drug discovery today. Classically, a number of drugs based on GPCRs have been developed for such different indications as cardiovascular, metabolic, neurodegenerative, psychiatric, and oncologic diseases. Owing to the restricted structural information on GPCRs, only limited exploration of structure-based drug design has been possible. Much effort has been dedicated to structural biology on GPCRs and very recently an X-ray structure of the beta2-adrenergic receptor was obtained. This breakthrough will certainly increase the efforts in structural biology on GPCRs and furthermore speed up and facilitate the drug discovery process." @default.
- W35537551 created "2016-06-24" @default.
- W35537551 creator A5052635748 @default.
- W35537551 date "2009-01-01" @default.
- W35537551 modified "2023-10-16" @default.
- W35537551 title "An Overview on GPCRs and Drug Discovery: Structure-Based Drug Design and Structural Biology on GPCRs" @default.
- W35537551 cites W1534908675 @default.
- W35537551 cites W1545792116 @default.
- W35537551 cites W1547225120 @default.
- W35537551 cites W1586315929 @default.
- W35537551 cites W1602512023 @default.
- W35537551 cites W1616806865 @default.
- W35537551 cites W166769851 @default.
- W35537551 cites W1838890896 @default.
- W35537551 cites W1880891411 @default.
- W35537551 cites W1966653081 @default.
- W35537551 cites W1968851198 @default.
- W35537551 cites W1971886200 @default.
- W35537551 cites W1972151663 @default.
- W35537551 cites W1974777098 @default.
- W35537551 cites W1978275988 @default.
- W35537551 cites W1979060714 @default.
- W35537551 cites W1980827675 @default.
- W35537551 cites W1981269287 @default.
- W35537551 cites W1984355679 @default.
- W35537551 cites W1991101726 @default.
- W35537551 cites W1992714668 @default.
- W35537551 cites W2005776302 @default.
- W35537551 cites W2010630721 @default.
- W35537551 cites W2014046162 @default.
- W35537551 cites W2015451804 @default.
- W35537551 cites W2019074781 @default.
- W35537551 cites W2021269933 @default.
- W35537551 cites W2023724239 @default.
- W35537551 cites W2023939486 @default.
- W35537551 cites W2025817112 @default.
- W35537551 cites W2027740042 @default.
- W35537551 cites W2028267773 @default.
- W35537551 cites W2030215768 @default.
- W35537551 cites W2034494253 @default.
- W35537551 cites W2036013134 @default.
- W35537551 cites W2037787858 @default.
- W35537551 cites W2041792559 @default.
- W35537551 cites W2042239308 @default.
- W35537551 cites W2042268377 @default.
- W35537551 cites W2045060141 @default.
- W35537551 cites W2050995501 @default.
- W35537551 cites W2052227833 @default.
- W35537551 cites W2052745304 @default.
- W35537551 cites W2054351735 @default.
- W35537551 cites W2056312165 @default.
- W35537551 cites W2060928316 @default.
- W35537551 cites W2061195966 @default.
- W35537551 cites W2062876104 @default.
- W35537551 cites W2062912306 @default.
- W35537551 cites W2063043885 @default.
- W35537551 cites W2065203967 @default.
- W35537551 cites W2072154498 @default.
- W35537551 cites W2072398405 @default.
- W35537551 cites W2075262579 @default.
- W35537551 cites W2078534481 @default.
- W35537551 cites W2078721878 @default.
- W35537551 cites W2080231167 @default.
- W35537551 cites W2081858805 @default.
- W35537551 cites W2083839784 @default.
- W35537551 cites W2087794637 @default.
- W35537551 cites W2089189332 @default.
- W35537551 cites W2090119198 @default.
- W35537551 cites W2090642099 @default.
- W35537551 cites W2092868643 @default.
- W35537551 cites W2104477830 @default.
- W35537551 cites W2108707223 @default.
- W35537551 cites W2110469184 @default.
- W35537551 cites W2110810808 @default.
- W35537551 cites W2114068014 @default.
- W35537551 cites W2122060463 @default.
- W35537551 cites W2124492456 @default.
- W35537551 cites W2136672278 @default.
- W35537551 cites W2146239303 @default.
- W35537551 cites W2147245370 @default.
- W35537551 cites W2149963584 @default.
- W35537551 cites W2151312020 @default.
- W35537551 cites W2155570846 @default.
- W35537551 cites W2159205729 @default.
- W35537551 cites W2161027162 @default.
- W35537551 cites W2164089619 @default.
- W35537551 cites W2337181279 @default.
- W35537551 cites W2417679656 @default.
- W35537551 cites W2952947350 @default.
- W35537551 cites W65178786 @default.
- W35537551 cites W88151061 @default.
- W35537551 doi "https://doi.org/10.1007/978-1-60327-317-6_4" @default.
- W35537551 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7122359" @default.
- W35537551 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19513641" @default.
- W35537551 hasPublicationYear "2009" @default.
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