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- W356656 abstract "Although it has been known that doxapram has stimulus effect on the carotid body (Mitchell and Herbert, 1975; Nishino, 1982), the mechanism has not yet been explained at the cellular or receptor level. Peers and Wyatt described the electrophysiological effects of doxapram on K+ channels on glomus cells and doxapram can inhibit the K+ current of the glomus cells (Peers, 1991; Wyatt and Peers, 1994). They forwarded a hypothesis that doxapram modulates carotid body chemoreception via the same signaling pathway as “the membrane model of O2 sensing” (for review see López- Barneo, 1996). KeywordsCarotid BodyFree SolutionBKca ChannelGlomus CellHypoxic Ventilatory ResponseThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves." @default.
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- W356656 date "2003-01-01" @default.
- W356656 modified "2023-10-02" @default.
- W356656 title "Doxapram Stimulates Carotid Body with Different Mechanisms from Hypoxic Chemotransduction" @default.
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- W356656 doi "https://doi.org/10.1007/978-1-4419-9280-2_16" @default.
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