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- W35760784 abstract "In Brief Purpose: To compare the preferential hyperacuity perimeter (PHP) with an Amsler grid in detection of age-related macular degeneration (AMD). Methods: Patients underwent refraction, visual acuity examination, PHP, Amsler grid examination, and macular photography. Results: One hundred fifty patients participated in the trial. Of 19 eyes with neovascular AMD, 19 (100%) were positive on the PHP, and 10 (53%), on the Amsler grid. Of 27 eyes with geographic atrophy, 26 (96%) were positive on the PHP, and 12 (44%), on the Amsler grid. Of 20 eyes with intermediate AMD, 14 (70%) were positive on the PHP, and 4 (20%), on the Amsler grid. Of 51 eyes with early AMD, 21 (41%) were positive on the PHP, and 4 (8%), on the Amsler grid. Of 33 eyes with no AMD, 6 (18%) were positive on the PHP, and none, on the Amsler grid. Thus, 80 (68%) of 117 patients with AMD had a positive PHP, while 30 (26%) had positive results of Amsler grid examination (P < 0.001, McNemar test). Conclusion: The PHP had greater sensitivity, although with a relatively high rate of false-positive results for healthy individuals, than the Amsler grid in detecting AMD-related lesions. The Preferential Hyperacuity Perimeter (PHP) has superior sensitivity compared to the Amsler grid in detecting age-related macular degeneration (AMD) lesions." @default.
- W35760784 created "2016-06-24" @default.
- W35760784 date "2005-04-01" @default.
- W35760784 modified "2023-09-25" @default.
- W35760784 title "RESULTS OF A MULTICENTER CLINICAL TRIAL TO EVALUATE THE PREFERENTIAL HYPERACUITY PERIMETER FOR DETECTION OF AGE-RELATED MACULAR DEGENERATION" @default.
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- W35760784 doi "https://doi.org/10.1097/00006982-200504000-00008" @default.
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