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- W35777660 abstract "Abstract The solid-state characterization of novel pharmaceutical compounds remains an important issue. Solid-state NMR is one of the techniques of choice to gain information when other techniques are not available. Knowledge of the molecular structure in the solid state can lead to better design and control the behaviour of the drug as it affects important properties such as solubility in aqueous medium. Many different NMR experiments can be performed to obtain either structural or dynamic information on very broad space and time ranges, respectively. Contrary to others techniques, not only crystalline material but also amorphous materials can be studied by SSNMR. These and other aspects make SSNMR a very powerful technique to obtain relevant information on solids pharmaceutical forms. We will discuss the SSNMR most common experiments used to investigate pharmaceutical compounds, including one- and two-dimensional experiments and relaxation time measurements. Additionally, we will mention some aspects of first principle calculation. Also we highlight the importance of NMR as a multinuclear technique. We will focus on SSNMR applied for characterization of new developed active pharmaceutical compounds and formulated drugs. We will pay attention to some particular topics as polymorphism, complexes with cyclodextrin and an emerging issue in pharmaceutical industry as it is the development of cocrystals. NMR crystallography is also discussed." @default.
- W35777660 created "2016-06-24" @default.
- W35777660 creator A5031983490 @default.
- W35777660 creator A5077527550 @default.
- W35777660 creator A5083483342 @default.
- W35777660 date "2014-01-01" @default.
- W35777660 modified "2023-10-18" @default.
- W35777660 title "Solid-State Nuclear Magnetic Resonance in Pharmaceutical Compounds" @default.
- W35777660 cites W1806328093 @default.
- W35777660 cites W1935894303 @default.
- W35777660 cites W1944192919 @default.
- W35777660 cites W1965200823 @default.
- W35777660 cites W1966910457 @default.
- W35777660 cites W1967100264 @default.
- W35777660 cites W1967571170 @default.
- W35777660 cites W1967998310 @default.
- W35777660 cites W1968713097 @default.
- W35777660 cites W1974292200 @default.
- W35777660 cites W1979621158 @default.
- W35777660 cites W1980626231 @default.
- W35777660 cites W1980913293 @default.
- W35777660 cites W1983469550 @default.
- W35777660 cites W1984009385 @default.
- W35777660 cites W1984442218 @default.
- W35777660 cites W1984535647 @default.
- W35777660 cites W1985517207 @default.
- W35777660 cites W1988225898 @default.
- W35777660 cites W1991182147 @default.
- W35777660 cites W1993889320 @default.
- W35777660 cites W1998647396 @default.
- W35777660 cites W1998781183 @default.
- W35777660 cites W2001010012 @default.
- W35777660 cites W2002738799 @default.
- W35777660 cites W2003172110 @default.
- W35777660 cites W2004500944 @default.
- W35777660 cites W2004649637 @default.
- W35777660 cites W2004744694 @default.
- W35777660 cites W2005981878 @default.
- W35777660 cites W2006430237 @default.
- W35777660 cites W2006608901 @default.
- W35777660 cites W2008286397 @default.
- W35777660 cites W2008740926 @default.
- W35777660 cites W2009048792 @default.
- W35777660 cites W2011502589 @default.
- W35777660 cites W2011616524 @default.
- W35777660 cites W2012373271 @default.
- W35777660 cites W2014982729 @default.
- W35777660 cites W2016879086 @default.
- W35777660 cites W2019816073 @default.
- W35777660 cites W2023601469 @default.
- W35777660 cites W2023630350 @default.
- W35777660 cites W2025047805 @default.
- W35777660 cites W2026195773 @default.
- W35777660 cites W2028000898 @default.
- W35777660 cites W2029561831 @default.
- W35777660 cites W2034056979 @default.
- W35777660 cites W2035262666 @default.
- W35777660 cites W2036562552 @default.
- W35777660 cites W2037178226 @default.
- W35777660 cites W2039035643 @default.
- W35777660 cites W2042107792 @default.
- W35777660 cites W2042628967 @default.
- W35777660 cites W2045824759 @default.
- W35777660 cites W2046161052 @default.
- W35777660 cites W2046499714 @default.
- W35777660 cites W2046984650 @default.
- W35777660 cites W2047382263 @default.
- W35777660 cites W2047478628 @default.
- W35777660 cites W2048179580 @default.
- W35777660 cites W2048830154 @default.
- W35777660 cites W2052046782 @default.
- W35777660 cites W2054118139 @default.
- W35777660 cites W2054233634 @default.
- W35777660 cites W2055516309 @default.
- W35777660 cites W2055559592 @default.
- W35777660 cites W2055737530 @default.
- W35777660 cites W2063875834 @default.
- W35777660 cites W2064605784 @default.
- W35777660 cites W2064625584 @default.
- W35777660 cites W2065661332 @default.
- W35777660 cites W2066654247 @default.
- W35777660 cites W2069032040 @default.
- W35777660 cites W2073275834 @default.
- W35777660 cites W2073456732 @default.
- W35777660 cites W2073634319 @default.
- W35777660 cites W2073887577 @default.
- W35777660 cites W2077850582 @default.
- W35777660 cites W2078202879 @default.
- W35777660 cites W2078319921 @default.
- W35777660 cites W2082076695 @default.
- W35777660 cites W2084840788 @default.
- W35777660 cites W2087125332 @default.
- W35777660 cites W2089419297 @default.
- W35777660 cites W2093701721 @default.
- W35777660 cites W2094095614 @default.
- W35777660 cites W2103688842 @default.
- W35777660 cites W2107746113 @default.
- W35777660 cites W2107846953 @default.