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- W358276176 abstract "This chapter focuses on the existing knowledge of the molecular basis for iron transport in the genera Staphylococcus, Streptococcus, and Bacillus. Staphylococci can be divided into two major groups: coagulase positive and coagulase negative. While coagulase-negative staphylococci (CoNS), notably Staphylococcus epidermidis, have come into prominence due to their opportunistic ability to colonize foreign medical devices, by far the most extensively studied staphylococcal species is coagulase-positive Staphylococcus aureus, owing to it being both a frequent and a highly versatile pathogen. The relative amounts of siderophore produced among various species and strains of Staphylococcus seem to vary remarkably and depends largely on culture conditions. The nomenclature of the genes is based on their homology to ferric hydroxamate transport proteins in Escherichia coli and Bacillus subtilis. For the most part, investigations into the ability of streptococci to transport iron have been limited to Streptococcus pneumoniae and Streptococcus pyogenes. B. anthracis is the causative agent of anthrax and has come into prominence recently due to its use as a biological weapon. The iron-restricted growth of B. cereus, a human pathogen, is inhibited by transferrin and lactoferrin but enhanced by hemoglobin, heme, and heme-albumin complexes. It is clear that molecular studies of iron transport systems in gram-positive bacteria, especially members of the genera Staphylococcus, Streptococcus, and Bacillus, are in their infancy." @default.
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- W358276176 date "2014-04-30" @default.
- W358276176 modified "2023-09-23" @default.
- W358276176 title "Staphylococcus, Streptococcus, and Bacillus" @default.
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- W358276176 doi "https://doi.org/10.1128/9781555816544.ch25" @default.
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