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- W35930697 abstract "1. Blood flow to the skeleton was measured by the 18F clearance method of Wootton, Reeve & Veall (1976) in 24 patients with untreated Paget's disease. In every patient but one, resting skeletal blood flow was increased. There was a significant positive correlation between skeletal blood flow and serum alkaline phosphatase and between skeletal blood flow and urinary total hydroxyproline excretion. 2. Fourteen patients were re-studied after they had received short-term (7 days or less) or long-term (7 weeks or more) calcitonin. Skeletal blood flow, alkaline phosphatase and urinary hydroxyproline excretion fell towards normal in every case. There was some evidence from the short-term studies that calcitonin produced a more rapid fall in skeletal blood flow than in alkaline phosphatase. 3. Glomerular filtration rate appeared to increase transiently in response to calcitonin." @default.
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- W35930697 date "1978-01-01" @default.
- W35930697 modified "2023-10-18" @default.
- W35930697 title "Skeletal Blood Flow in Paget's Disease of Bone and its Response to Calcitonin Therapy" @default.
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- W35930697 doi "https://doi.org/10.1042/cs0540069" @default.
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