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• W361569648 abstract "Pyridoxal-P plays a major role in the short term regulation of γ-aminobutyric acid (GABA) synthesis in brain, as the GABA-synthesizing enzyme glutamate decarboxylase (GAD) is regulated in part by a tightly controlled cycle that interconverts the hold- and apoenzyme. This mechanism explains the sensitivity of brain GABA levels to vitamin B6 deficiency and very likely contributes to the enhanced seizure susceptibility that is a prominent symptom of vitamin B6 deficiency in animals and humans." @default.
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• W361569648 date "1994-01-01" @default.
• W361569648 modified "2023-09-23" @default.
• W361569648 title "Pyridoxal Phosphate, GABA and Seizure Susceptibility" @default.
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• W361569648 doi "https://doi.org/10.1007/978-3-0348-7393-2_54" @default.
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