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- W36267002 abstract "Leishmania parasites cycle between sand fly vectors and mammalian hosts, thus experiencing a wide range of temperatures and pH values as well as coping with oxidative stress. These environmental stress conditions trigger stage differentiation and a pattern of developmental gene expression. Despite their ability to survive extreme conditions, the parasites are sensitive to temperatures above a certain threshold, above which cell death occurs. Stage-specific gene regulation occurs exclusively by posttranscriptional mechanisms, including RNA processing, stability, and translation, with the various heat shock genes serving as ideal model systems for this unique group of ancient eukaryotes." @default.
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- W36267002 date "2007-01-01" @default.
- W36267002 modified "2023-10-18" @default.
- W36267002 title "Leishmania, Stress Response in" @default.
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- W36267002 doi "https://doi.org/10.1016/b978-012373947-6.00236-1" @default.
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