FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W36574037> ?p ?o ?g. }

• W36574037 endingPage "655" @default.
• W36574037 startingPage "650" @default.
• W36574037 abstract "Etomidate has a neutral hemodynamic profile which has made it an attractive medication for emergent intubation. Despite theoretical advantages of etomidate administration in the trauma patient, there are incomplete data to support its use. This study examined the association of etomidate use for emergent intubation in traumatic illness with patient mortality. This is a historical cohort study using the Nova Scotia Trauma Registry. It included all major adult trauma patients who required tracheal intubation at the Queen Elizabeth II Health Sciences Centre in Halifax, Canada from January 23, 2000 to March 25, 2012. Prospectively recorded data were analyzed, including patient demographics, presence of comorbidities, trauma specific variables, admission and discharge vitals, length of stay in the intensive care unit (ICU) and hospital, mechanical ventilation-free days, and mortality. Associations between the use of etomidate and 28-day mortality are presented as odds ratios. Multivariable logistic regression models were created adjusting for age, injury severity score (ISS), sex, comorbidities, presence of traumatic brain injury, and injury type. The effects of etomidate on other relevant outcome variables were assessed using unpaired Student’s t-tests. Three hundred eight patients were included in the study, and there were 42 deaths. Patients receiving etomidate were similar to those who did not, including ISS and pre-intubation blood pressure. The 28-day mortality was 18.7% in the etomidate group and 11.1% in the non-etomidate group (odds ratio = 1.85; 95% confidence interval [CI] 0.96 to 3.57; P = 0.07). After adjustment for age, female sex, ISS, and comorbidity, the odds ratio was 1.94 (95% CI 0.87 to 4.37; P = 0.11). There were no differences between the two groups in ICU length of stay, hospital length of stay, or number of ventilation-free days. The association between use of a single dose of etomidate for emergency tracheal intubation in the trauma patient and mortality is inconclusive. Etomidate administration should be used with caution in trauma patients requiring tracheal intubation. Further data are required to determine the safety and risk-benefit of etomidate use in this patient population." @default.
• W36574037 created "2016-06-24" @default.
• W36574037 creator A5010901555 @default.
• W36574037 creator A5075565472 @default.
• W36574037 date "2014-04-11" @default.
• W36574037 modified "2023-10-18" @default.
• W36574037 title "The impact of etomidate on mortality in trauma patients" @default.
• W36574037 cites W1996672107 @default.
• W36574037 cites W1997114027 @default.
• W36574037 cites W2013124743 @default.
• W36574037 cites W2024439629 @default.
• W36574037 cites W2058391271 @default.
• W36574037 cites W2071334706 @default.
• W36574037 cites W2074117478 @default.
• W36574037 cites W2081102884 @default.
• W36574037 cites W2084962044 @default.
• W36574037 cites W2097513009 @default.
• W36574037 cites W2129877062 @default.
• W36574037 cites W2134236406 @default.
• W36574037 cites W2135414391 @default.
• W36574037 cites W2138038058 @default.
• W36574037 cites W2139776082 @default.
• W36574037 cites W2159850762 @default.
• W36574037 cites W2169011232 @default.
• W36574037 cites W4234196640 @default.
• W36574037 doi "https://doi.org/10.1007/s12630-014-0161-6" @default.
• W36574037 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24723214" @default.
• W36574037 hasPublicationYear "2014" @default.
• W36574037 type Work @default.
• W36574037 sameAs 36574037 @default.
• W36574037 citedByCount "21" @default.
• W36574037 countsByYear W365740372014 @default.
• W36574037 countsByYear W365740372015 @default.
• W36574037 countsByYear W365740372017 @default.
• W36574037 countsByYear W365740372018 @default.
• W36574037 countsByYear W365740372019 @default.
• W36574037 countsByYear W365740372021 @default.
• W36574037 countsByYear W365740372022 @default.
• W36574037 countsByYear W365740372023 @default.
• W36574037 crossrefType "journal-article" @default.
• W36574037 hasAuthorship W36574037A5010901555 @default.
• W36574037 hasAuthorship W36574037A5075565472 @default.
• W36574037 hasBestOaLocation W365740371 @default.
• W36574037 hasConcept C126322002 @default.
• W36574037 hasConcept C156957248 @default.
• W36574037 hasConcept C190385971 @default.
• W36574037 hasConcept C194828623 @default.
• W36574037 hasConcept C2776277131 @default.
• W36574037 hasConcept C2776376669 @default.
• W36574037 hasConcept C2778716859 @default.
• W36574037 hasConcept C2779676917 @default.
• W36574037 hasConcept C3017944768 @default.
• W36574037 hasConcept C42219234 @default.
• W36574037 hasConcept C44249647 @default.
• W36574037 hasConcept C71924100 @default.
• W36574037 hasConcept C85004164 @default.
• W36574037 hasConceptScore W36574037C126322002 @default.
• W36574037 hasConceptScore W36574037C156957248 @default.
• W36574037 hasConceptScore W36574037C190385971 @default.
• W36574037 hasConceptScore W36574037C194828623 @default.
• W36574037 hasConceptScore W36574037C2776277131 @default.
• W36574037 hasConceptScore W36574037C2776376669 @default.
• W36574037 hasConceptScore W36574037C2778716859 @default.
• W36574037 hasConceptScore W36574037C2779676917 @default.
• W36574037 hasConceptScore W36574037C3017944768 @default.
• W36574037 hasConceptScore W36574037C42219234 @default.
• W36574037 hasConceptScore W36574037C44249647 @default.
• W36574037 hasConceptScore W36574037C71924100 @default.
• W36574037 hasConceptScore W36574037C85004164 @default.
• W36574037 hasIssue "7" @default.
• W36574037 hasLocation W365740371 @default.
• W36574037 hasLocation W365740372 @default.
• W36574037 hasOpenAccess W36574037 @default.
• W36574037 hasPrimaryLocation W365740371 @default.
• W36574037 hasRelatedWork W1558580122 @default.
• W36574037 hasRelatedWork W1985328162 @default.
• W36574037 hasRelatedWork W2018880237 @default.
• W36574037 hasRelatedWork W2025180791 @default.
• W36574037 hasRelatedWork W2107732923 @default.
• W36574037 hasRelatedWork W2290337589 @default.
• W36574037 hasRelatedWork W2323035194 @default.
• W36574037 hasRelatedWork W2337048672 @default.
• W36574037 hasRelatedWork W2897270174 @default.
• W36574037 hasRelatedWork W3032140457 @default.
• W36574037 hasVolume "61" @default.
• W36574037 isParatext "false" @default.
• W36574037 isRetracted "false" @default.
• W36574037 magId "36574037" @default.
• W36574037 workType "article" @default.