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- W36639130 abstract "Optical signals related to membrane potential have been obtained with several hundred different dyes and thus, one might not expect a single mechanism to be responsible for all of the signals. The dye signals can be divided into two types with basically different mechanisms. It is convenient that dyes that work through the two types of mechanism have in turn been used in separate kinds of applications. In one situation, the optical signals appear to arise from dye that is membrane bound. These optical signals follow changes in membrane potential with time constants of less than 0.01 ms and are, thus, suited for optical monitoring of action potentials and other rapid potential changes that occur in excitable cells. This kind of signal has been termed as fast signal. Optical signals from a different group of dyes originate from the re-equilibration of charged, permeant dye molecules across the cell membrane when the membrane potential changes." @default.
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- W36639130 date "1981-01-01" @default.
- W36639130 modified "2023-09-27" @default.
- W36639130 title "OPTICAL MONITORING OF MEMBRANE POTENTIAL: SIMULTANEOUS DETECTION OF ACTIVITY IN MANY NEURONS" @default.
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- W36639130 doi "https://doi.org/10.1016/b978-0-08-026816-3.50026-2" @default.
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