FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W36670911> ?p ?o ?g. }

• W36670911 endingPage "88" @default.
• W36670911 startingPage "83" @default.
• W36670911 abstract "Alpha-thalassemia is one of the most common hemoglobin genetic abnormalities and is caused by the reduced or absent production of the alpha globin chains. Alpha-thalassemia is prevalent in tropical and subtropical world regions where malaria was and still is epidemic, but as a consequence of the recent massive population migrations, alpha-thalassemia has become a relatively common clinical problem in North America, North Europe, and Australia. Alpha-thalassemia is very heterogeneous at a clinical and molecular level. Four clinical conditions of increased severity are recognized: the silent carrier state, the alpha-thalassemia trait, the intermediate form of hemoglobin H disease, and the hemoglobin Bart hydrops fetalis syndrome that is lethal in utero or soon after birth.Alpha-thalassemia is caused most frequently by deletions involving one or both alpha globin genes and less commonly by nondeletional defects. A large number of alpha-thalassemia alleles have been described and their interaction results in the wide spectrum of hematological and clinical phenotypes. Genotype-phenotype correlation has been only partly clarified. Carriers of alpha-thalassemia do not need any treatment. Usually, patients with hemoglobin H disease are clinically well and survive without any treatment, but occasional red blood cell transfusions may be needed if the hemoglobin level suddenly drops because of hemolytic or aplastic crisis likely due to viral infections. Hemoglobin Bart hydrops fetalis syndrome currently has no effective treatment although attempts at intrauterine transfusion and hematopoietic stem cell transplantation have been made. Genet Med 2011:13(2):83–88." @default.
• W36670911 created "2016-06-24" @default.
• W36670911 creator A5004204696 @default.
• W36670911 creator A5061262571 @default.
• W36670911 date "2011-02-01" @default.
• W36670911 modified "2023-10-16" @default.
• W36670911 title "Alpha-thalassemia" @default.
• W36670911 cites W1774432692 @default.
• W36670911 cites W1966463497 @default.
• W36670911 cites W1986988703 @default.
• W36670911 cites W1989081581 @default.
• W36670911 cites W1989862733 @default.
• W36670911 cites W2006455644 @default.
• W36670911 cites W2008456630 @default.
• W36670911 cites W2018205338 @default.
• W36670911 cites W2019869394 @default.
• W36670911 cites W2022737053 @default.
• W36670911 cites W2025381784 @default.
• W36670911 cites W2027867325 @default.
• W36670911 cites W2038731090 @default.
• W36670911 cites W2044757035 @default.
• W36670911 cites W2047187117 @default.
• W36670911 cites W2048447535 @default.
• W36670911 cites W2050764082 @default.
• W36670911 cites W2054076270 @default.
• W36670911 cites W2059180983 @default.
• W36670911 cites W2071347618 @default.
• W36670911 cites W2075685244 @default.
• W36670911 cites W2083910426 @default.
• W36670911 cites W2084169030 @default.
• W36670911 cites W2087542095 @default.
• W36670911 cites W2092775854 @default.
• W36670911 cites W2102052544 @default.
• W36670911 cites W2109717603 @default.
• W36670911 cites W2112499150 @default.
• W36670911 cites W2116176481 @default.
• W36670911 cites W2121621767 @default.
• W36670911 cites W2126384617 @default.
• W36670911 cites W2147128837 @default.
• W36670911 cites W2151716129 @default.
• W36670911 cites W2157311952 @default.
• W36670911 doi "https://doi.org/10.1097/gim.0b013e3181fcb468" @default.
• W36670911 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21381239" @default.
• W36670911 hasPublicationYear "2011" @default.
• W36670911 type Work @default.
• W36670911 sameAs 36670911 @default.
• W36670911 citedByCount "127" @default.
• W36670911 countsByYear W366709112012 @default.
• W36670911 countsByYear W366709112013 @default.
• W36670911 countsByYear W366709112014 @default.
• W36670911 countsByYear W366709112015 @default.
• W36670911 countsByYear W366709112016 @default.
• W36670911 countsByYear W366709112017 @default.
• W36670911 countsByYear W366709112018 @default.
• W36670911 countsByYear W366709112019 @default.
• W36670911 countsByYear W366709112020 @default.
• W36670911 countsByYear W366709112021 @default.
• W36670911 countsByYear W366709112022 @default.
• W36670911 countsByYear W366709112023 @default.
• W36670911 crossrefType "journal-article" @default.
• W36670911 hasAuthorship W36670911A5004204696 @default.
• W36670911 hasAuthorship W36670911A5061262571 @default.
• W36670911 hasBestOaLocation W366709111 @default.
• W36670911 hasConcept C104317684 @default.
• W36670911 hasConcept C126322002 @default.
• W36670911 hasConcept C135763542 @default.
• W36670911 hasConcept C172680121 @default.
• W36670911 hasConcept C203014093 @default.
• W36670911 hasConcept C2777674756 @default.
• W36670911 hasConcept C2777799968 @default.
• W36670911 hasConcept C2777940137 @default.
• W36670911 hasConcept C2778548071 @default.
• W36670911 hasConcept C2779234561 @default.
• W36670911 hasConcept C2908647359 @default.
• W36670911 hasConcept C54355233 @default.
• W36670911 hasConcept C71924100 @default.
• W36670911 hasConcept C86803240 @default.
• W36670911 hasConcept C99454951 @default.
• W36670911 hasConceptScore W36670911C104317684 @default.
• W36670911 hasConceptScore W36670911C126322002 @default.
• W36670911 hasConceptScore W36670911C135763542 @default.
• W36670911 hasConceptScore W36670911C172680121 @default.
• W36670911 hasConceptScore W36670911C203014093 @default.
• W36670911 hasConceptScore W36670911C2777674756 @default.
• W36670911 hasConceptScore W36670911C2777799968 @default.
• W36670911 hasConceptScore W36670911C2777940137 @default.
• W36670911 hasConceptScore W36670911C2778548071 @default.
• W36670911 hasConceptScore W36670911C2779234561 @default.
• W36670911 hasConceptScore W36670911C2908647359 @default.
• W36670911 hasConceptScore W36670911C54355233 @default.
• W36670911 hasConceptScore W36670911C71924100 @default.
• W36670911 hasConceptScore W36670911C86803240 @default.
• W36670911 hasConceptScore W36670911C99454951 @default.
• W36670911 hasIssue "2" @default.
• W36670911 hasLocation W366709111 @default.
• W36670911 hasLocation W366709112 @default.
• W36670911 hasOpenAccess W36670911 @default.
• W36670911 hasPrimaryLocation W366709111 @default.

• next