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- W3668475 abstract "This chapter discusses the epidemiology, pathologic classification, genetics, clinical features, diagnostic evaluation, staging, and treatments of Rhabdomyosarcoma. It is a tumor of striated muscle, most common pediatric soft-tissue sarcoma, and is the third common solid tumor. The histologic subtypes with reference to their frequency, morphology, site of origin, and age distribution are also discussed. Specific assays may be necessary to aid in the differential diagnosis of rhabdomyosarcoma from the other small round cell tumors. These assays include: electron microscopy, immunocytochemistry, and cytogenetics. The disease may occur in any anatomic location of the body where there is skeletal muscle, as well as in sites where no skeletal muscle is found. The most frequent sign is a mass. Specific clinical manifestations vary with the site of origin of the primary lesion; thereby, head and neck primary tumor is important clinical feature of parameningeal. The diagnostic evaluation of the primary tumor and the extent of metastatic disease consist of the following: complete history, physical examination, complete blood count, urinalysis, serum electrolytes, blood urea nitrogen, and magnetic resonance imaging or computed tomography of primary lesion. Local control is accomplished using surgery or radiotherapy. Systemic control is accomplished with chemotherapy. Patients with localized disease require systemic therapy to eradicate micrometastatic disease typically present at diagnosis." @default.
- W3668475 created "2016-06-24" @default.
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- W3668475 date "2011-01-01" @default.
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- W3668475 title "Rhabdomyosarcoma and Other Soft-Tissue Sarcomas" @default.
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- W3668475 doi "https://doi.org/10.1016/b978-0-12-375154-6.00024-0" @default.
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