Matches in SemOpenAlex for { <https://semopenalex.org/work/W36714749> ?p ?o ?g. }
- W36714749 endingPage "173" @default.
- W36714749 startingPage "133" @default.
- W36714749 abstract "AbstractThis chapter addresses three coordinated chronobiological studies demonstrating the convergence of experimental observations, fine-grained spatio-temporal modelling, and predictive simulation. Due to the discrete manner of molecular assembly in cell signalling and gene regulation, we define a framework of membrane systems equipped with discretised forms of reaction kinetics in concert with variable intramolecular structures. Our first study is dedicated to circadian clocks inducing daily biological rhythms. As an inspiring example, the KaiABC core oscillator reaches its functionality by cyclically varying protein structures. Within our second study, we present a meta-model of an entire circadian clockwork able to adapt its oscillation to an external stimulus in terms of a frequency control system acting in a phase-locked loop. Substrate concentration courses resulting from gene expression reflect its oscillatory behaviour utilised in a periodical trigger for subsequent processes. In this context, our third study cytometrically quantifies the dynamical behaviour of a bistable toggle switch resulting from mutual gene regulation.KeywordsCircadian ClockGene Regulatory NetworkMembrane SystemDerivation TreeReaction RuleThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves." @default.
- W36714749 created "2016-06-24" @default.
- W36714749 creator A5007754301 @default.
- W36714749 creator A5018987403 @default.
- W36714749 creator A5020738003 @default.
- W36714749 creator A5043294312 @default.
- W36714749 creator A5050599351 @default.
- W36714749 creator A5051064408 @default.
- W36714749 creator A5072305924 @default.
- W36714749 creator A5079511915 @default.
- W36714749 creator A5090620874 @default.
- W36714749 date "2013-12-18" @default.
- W36714749 modified "2023-10-16" @default.
- W36714749 title "Membrane Systems and Tools Combining Dynamical Structures with Reaction Kinetics for Applications in Chronobiology" @default.
- W36714749 cites W111157985 @default.
- W36714749 cites W1461410628 @default.
- W36714749 cites W1512974087 @default.
- W36714749 cites W1540140960 @default.
- W36714749 cites W1599969036 @default.
- W36714749 cites W1603696475 @default.
- W36714749 cites W162935903 @default.
- W36714749 cites W1886596768 @default.
- W36714749 cites W1971327350 @default.
- W36714749 cites W1971709523 @default.
- W36714749 cites W1984886691 @default.
- W36714749 cites W1986553481 @default.
- W36714749 cites W1990903593 @default.
- W36714749 cites W2001799714 @default.
- W36714749 cites W2007132436 @default.
- W36714749 cites W2011909181 @default.
- W36714749 cites W2013775609 @default.
- W36714749 cites W2017258374 @default.
- W36714749 cites W2019465613 @default.
- W36714749 cites W2035571475 @default.
- W36714749 cites W2037298848 @default.
- W36714749 cites W2047331390 @default.
- W36714749 cites W2057225682 @default.
- W36714749 cites W2063821729 @default.
- W36714749 cites W2064397441 @default.
- W36714749 cites W2073390681 @default.
- W36714749 cites W2085061065 @default.
- W36714749 cites W2086131827 @default.
- W36714749 cites W2091478534 @default.
- W36714749 cites W2096083200 @default.
- W36714749 cites W2123584715 @default.
- W36714749 cites W2126922170 @default.
- W36714749 cites W2130611503 @default.
- W36714749 cites W2134759932 @default.
- W36714749 cites W2139546509 @default.
- W36714749 cites W2140711153 @default.
- W36714749 cites W2145600675 @default.
- W36714749 cites W2155418451 @default.
- W36714749 cites W2158708642 @default.
- W36714749 cites W2159356109 @default.
- W36714749 cites W2163493106 @default.
- W36714749 cites W2164211912 @default.
- W36714749 cites W2165700291 @default.
- W36714749 cites W2294163674 @default.
- W36714749 cites W2487950906 @default.
- W36714749 cites W2495992444 @default.
- W36714749 cites W39861160 @default.
- W36714749 cites W4233330764 @default.
- W36714749 cites W4251610473 @default.
- W36714749 cites W4253060067 @default.
- W36714749 cites W582331238 @default.
- W36714749 doi "https://doi.org/10.1007/978-3-319-03191-0_5" @default.
- W36714749 hasPublicationYear "2013" @default.
- W36714749 type Work @default.
- W36714749 sameAs 36714749 @default.
- W36714749 citedByCount "5" @default.
- W36714749 countsByYear W367147492014 @default.
- W36714749 countsByYear W367147492015 @default.
- W36714749 countsByYear W367147492017 @default.
- W36714749 countsByYear W367147492021 @default.
- W36714749 crossrefType "book-chapter" @default.
- W36714749 hasAuthorship W36714749A5007754301 @default.
- W36714749 hasAuthorship W36714749A5018987403 @default.
- W36714749 hasAuthorship W36714749A5020738003 @default.
- W36714749 hasAuthorship W36714749A5043294312 @default.
- W36714749 hasAuthorship W36714749A5050599351 @default.
- W36714749 hasAuthorship W36714749A5051064408 @default.
- W36714749 hasAuthorship W36714749A5072305924 @default.
- W36714749 hasAuthorship W36714749A5079511915 @default.
- W36714749 hasAuthorship W36714749A5090620874 @default.
- W36714749 hasConcept C112795245 @default.
- W36714749 hasConcept C121332964 @default.
- W36714749 hasConcept C121446783 @default.
- W36714749 hasConcept C1276947 @default.
- W36714749 hasConcept C139425391 @default.
- W36714749 hasConcept C151730666 @default.
- W36714749 hasConcept C169760540 @default.
- W36714749 hasConcept C171250308 @default.
- W36714749 hasConcept C185592680 @default.
- W36714749 hasConcept C186060115 @default.
- W36714749 hasConcept C192562407 @default.
- W36714749 hasConcept C2778439541 @default.
- W36714749 hasConcept C2779343474 @default.
- W36714749 hasConcept C41008148 @default.