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- W370529846 abstract "Testis-specific protease 50(TSP50) has been identified as a testis-specific protein that is expressed ab- normally in most human breast cancer samples, which makes it an attractive molecular marker and a potential target for diagnosis and therapy. In the present study, we prepared a panel of monoclonal antibodies(mAbs) with high speci- ficity and sensitivity against TSP50 by hybridoma method and characterized them by ELISA, Western blot, immu- nofluroescence and immunohistochemical analyses. The results show that all of the 9 different clones can specifically bind to TSP50. The mAbs against TSP50 we generated could be good tools for both basic and clinical studies. Keywords Biomarker; Breast cancer; Monoclonal antibody; Testis-specific protease 50 Article ID 1005-9040(2009)-04-483-04" @default.
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- W370529846 date "2009-01-01" @default.
- W370529846 modified "2023-09-27" @default.
- W370529846 title "Development and Characterization of Monoclonal Antibody Specifically Against TSP50" @default.
- W370529846 hasPublicationYear "2009" @default.
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