Matches in SemOpenAlex for { <https://semopenalex.org/work/W37209405> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W37209405 endingPage "5" @default.
- W37209405 startingPage "572" @default.
- W37209405 abstract "To establish rapid urease test utility for initial diagnosis of Helicobacter pylori infection in gastric ulcer patients and to determine the best site for sampling for gastric biopsies.Seventy consecutive gastric ulcer patients were prospectively studied. All these patients underwent three biopsies from both antrum and body (two for hematoxylin-eosin staining and one for rapid urease test -Jatrox H. p. Test-). Likewise, IgG ELISA serology and 13C-urea breath test were carried out. Gold standard for H. pylori infection was defined as two or more tests (i.e., histology, serology, breath test) with positive results.Rapid urease test yielded 96.8% sensitivity (95% CI = 89-99%) and 100% (66-100%) specificity when using biopsy specimens from the body, with identical results when biopsy specimens from both antrum and body were considered together. However, when only biopsy specimens from the antrum were used, sensitivity dropped to 72.6% (60-82%) and specificity was 100% (66-100%). As far as concordance between rapid urease test and histology is concerned, we found a proportion of positive agreement of 0.78 for the antrum, with 0.46 kappa statistic (P < 0.0001) and 15 McNemar statistic (P < 0.0001). For the gastric body, proportion of positive agreement was 0.98, with 0.94 kappa statistic (P < 0.0001) and 1 McNemar statistic (P = 0.3). Larger (P < 0.01) prevalence of both glandular atrophy (17.8%, 11-28%) and intestinal metaplasia (68.5%, 57-78%) was observed in the antrum in comparison with that in the body (4.1%, 1-11%; and 16.4%, 10-26%, respectively).Biopsy specimens from the body should always be obtained when the rapid urease test is performed to diagnose H. pylori infection in gastric ulcer, since this procedure is less accurate when biopsy specimens from the antrum are used, probably due to larger prevalence of both glandular atrophy and intestinal metaplasia in the latter site. Likewise, it seems that rapid urease test from body biopsies is sufficient to reach a reliable infection diagnosis in gastric ulcer patients as this procedure performed with antrum biopsies fails to improve its overall results." @default.
- W37209405 created "2016-06-24" @default.
- W37209405 creator A5014254734 @default.
- W37209405 creator A5014925928 @default.
- W37209405 creator A5029278372 @default.
- W37209405 creator A5035064260 @default.
- W37209405 creator A5037356434 @default.
- W37209405 creator A5061349570 @default.
- W37209405 creator A5075052827 @default.
- W37209405 creator A5088280306 @default.
- W37209405 date "2002-05-09" @default.
- W37209405 modified "2023-09-27" @default.
- W37209405 title "Rapid urease test utility for Helicobacter pylori infection diagnosis in gastric ulcer disease." @default.
- W37209405 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11995500" @default.
- W37209405 hasPublicationYear "2002" @default.
- W37209405 type Work @default.
- W37209405 sameAs 37209405 @default.
- W37209405 citedByCount "17" @default.
- W37209405 countsByYear W372094052012 @default.
- W37209405 countsByYear W372094052014 @default.
- W37209405 countsByYear W372094052015 @default.
- W37209405 countsByYear W372094052016 @default.
- W37209405 countsByYear W372094052017 @default.
- W37209405 countsByYear W372094052018 @default.
- W37209405 countsByYear W372094052021 @default.
- W37209405 crossrefType "journal-article" @default.
- W37209405 hasAuthorship W37209405A5014254734 @default.
- W37209405 hasAuthorship W37209405A5014925928 @default.
- W37209405 hasAuthorship W37209405A5029278372 @default.
- W37209405 hasAuthorship W37209405A5035064260 @default.
- W37209405 hasAuthorship W37209405A5037356434 @default.
- W37209405 hasAuthorship W37209405A5061349570 @default.
- W37209405 hasAuthorship W37209405A5075052827 @default.
- W37209405 hasAuthorship W37209405A5088280306 @default.
- W37209405 hasConcept C105795698 @default.
- W37209405 hasConcept C126322002 @default.
- W37209405 hasConcept C142724271 @default.
- W37209405 hasConcept C159654299 @default.
- W37209405 hasConcept C186282968 @default.
- W37209405 hasConcept C203014093 @default.
- W37209405 hasConcept C2775934546 @default.
- W37209405 hasConcept C2776409635 @default.
- W37209405 hasConcept C2778677798 @default.
- W37209405 hasConcept C2780708398 @default.
- W37209405 hasConcept C33923547 @default.
- W37209405 hasConcept C45189115 @default.
- W37209405 hasConcept C57742111 @default.
- W37209405 hasConcept C71924100 @default.
- W37209405 hasConcept C90924648 @default.
- W37209405 hasConceptScore W37209405C105795698 @default.
- W37209405 hasConceptScore W37209405C126322002 @default.
- W37209405 hasConceptScore W37209405C142724271 @default.
- W37209405 hasConceptScore W37209405C159654299 @default.
- W37209405 hasConceptScore W37209405C186282968 @default.
- W37209405 hasConceptScore W37209405C203014093 @default.
- W37209405 hasConceptScore W37209405C2775934546 @default.
- W37209405 hasConceptScore W37209405C2776409635 @default.
- W37209405 hasConceptScore W37209405C2778677798 @default.
- W37209405 hasConceptScore W37209405C2780708398 @default.
- W37209405 hasConceptScore W37209405C33923547 @default.
- W37209405 hasConceptScore W37209405C45189115 @default.
- W37209405 hasConceptScore W37209405C57742111 @default.
- W37209405 hasConceptScore W37209405C71924100 @default.
- W37209405 hasConceptScore W37209405C90924648 @default.
- W37209405 hasIssue "44" @default.
- W37209405 hasLocation W372094051 @default.
- W37209405 hasOpenAccess W37209405 @default.
- W37209405 hasPrimaryLocation W372094051 @default.
- W37209405 hasRelatedWork W1537613630 @default.
- W37209405 hasRelatedWork W1996247412 @default.
- W37209405 hasRelatedWork W2024034435 @default.
- W37209405 hasRelatedWork W2073961265 @default.
- W37209405 hasRelatedWork W2140179011 @default.
- W37209405 hasRelatedWork W2299623586 @default.
- W37209405 hasRelatedWork W2380613912 @default.
- W37209405 hasRelatedWork W2406874947 @default.
- W37209405 hasRelatedWork W2407430416 @default.
- W37209405 hasRelatedWork W2417154567 @default.
- W37209405 hasVolume "49" @default.
- W37209405 isParatext "false" @default.
- W37209405 isRetracted "false" @default.
- W37209405 magId "37209405" @default.
- W37209405 workType "article" @default.