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- W37339982 abstract "There are many potential mechanisms of peripheral nerve impairment by a monoclonal IgG dysglobulinemia. In this study, using electron microscopy, we observed widening of the myelin lamellae comparable to that commonly described in IgM neuropathies with antimyelin-associated glycoprotein activity. Such features have yet to be described in IgG neuropathies. In addition, we observed deposits of a granular material in the interstitial tissue of the nerve. By immunoelectron microscopy, we demonstrated the presence of the IgG in the lesions of myelin and the endoneurial space. A direct link between monoclonal dysglobulinemia (regardless of type) and polyneuropathy should be confirmed by nerve biopsy, because the result may influence treatment." @default.
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- W37339982 date "2005-05-01" @default.
- W37339982 modified "2023-09-23" @default.
- W37339982 title "IgG Neuropathy: An Immunoelectron Microscopic Study" @default.
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- W37339982 doi "https://doi.org/10.1093/jnen/64.5.386" @default.
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