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- W37669962 abstract "Radiation therapy has been effectively utilized in the management of prostate cancer since the early 1900s. Initially, techniques to apply radiotherapy to the prostate utilized implanted radium either transurethrally, transperineally, or transrectally. Although tumor shrinkage occurred, side-effects on adjacent organs limited its benefit. In the 1950s, high-energy supervoltage external beam therapy was introduced by Bagshaw et al. (1965) to the treatment armamentarium. Supervoltage external beam radiotherapy produced marked improvements in tumor control and survival rates without the previously limiting side-effects. Today, radiotherapy continues to play a central role in the management of prostate cancer along with observation, radical prostatectomy and hormonal therapy. As with surgery and other forms of therapy presently available, controversy exists about the long-term efficacy. Prostate cancer is rather unusual in that the disease process is so protracted it is often difficult to ascertain whether a specified therapy has been effective or whether the disease process was not destined to be aggressive." @default.
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- W37669962 date "1996-01-01" @default.
- W37669962 modified "2023-09-28" @default.
- W37669962 title "Surgical Salvage Options in Patients with Recurrent Tumor Following Radiotherapy" @default.
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- W37669962 doi "https://doi.org/10.1007/978-3-642-60956-5_13" @default.
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