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- W37784014 abstract "No AccessJournal of Urology1 Oct 1981Genetics of Undescended Testis A. Czeizel, E. Erödi, and J. Tóth A. CzeizelA. Czeizel More articles by this author , E. ErödiE. Erödi More articles by this author , and J. TóthJ. Tóth More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)54610-8AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail We present our study of the genetics of undescended testes. The occurrence of undescended testes could be confirmed in 1.5 to 4.0 per cent of the fathers and in 6.2 per cent of the brothers of index patients with true undescended testes. The pattern of the familial cluster fits into the gaussian-additive-multifactorial-threshold program. The value of heritability for the first degree male relatives is 0.67 plus or minus 0.16. In siblings of index patients with undescended testes other congenital abnormalities do not occur more often. Bilateral (more severe) undescended testes are associated with a higher recurrence risk for siblings. The nosological identity of unilateral and bilateral undescended testes cases was borne out by the family study data. The mothers of index patients with undescended testes have shorter menses and a delay in menarche. Thus, the pituitary hypogonadism of mothers seems to be a predisposing factor for undescended testes in their sons. © 1981 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited ByWEIDNER I, MOLLER H, JENSEN T and SKAKKEBAEK N (2018) RISK FACTORS FOR CRYPTORCHIDISM AND HYPOSPADIASJournal of Urology, VOL. 161, NO. 5, (1606-1609), Online publication date: 1-May-1999.WIENER J, MARCELLI M, GONZALES E, ROTH D and LAMB D (2018) ANDROGEN RECEPTOR GENE ALTERATIONS ARE NOT ASSOCIATED WITH ISOLATED CRYPTORCHIDISMJournal of Urology, VOL. 160, NO. 3 Part 1, (863-865), Online publication date: 1-Sep-1998. Volume 126Issue 4October 1981Page: 528-529 Advertisement Copyright & Permissions© 1981 by The American Urological Association Education and Research, Inc.MetricsAuthor Information A. Czeizel More articles by this author E. Erödi More articles by this author J. Tóth More articles by this author Expand All Advertisement Loading ..." @default.
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- W37784014 title "Genetics of Undescended Testis" @default.
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