Matches in SemOpenAlex for { <https://semopenalex.org/work/W37790948> ?p ?o ?g. }
- W37790948 abstract "Paratuberculosis, also known as Johne’s disease, is caused by oral uptake of Mycobacterium avium subspecies paratuberculosis (MAP) from the environment. MAP causes granulomatous lesions in the distal part of the ileum in domestic and wild ruminants.Ileal lesions limit sufficient nutrient uptake leading to weight loss and additionally, in animals used for dairy production, infection with paratuberculosis leads to decreased milk production and fertility. In the Dutch Holstein-Friesian dairy cattle population, prevalence of paratuberculosis based on a positive ELISA test in milk was 46.7% on the herd level and 2.4% on the animal level in 2008. Prevalence of paratuberculosis in dairy goat herds is unknown but suspected to be higher than in cattle herds based on clinical and routine pathological observations.The aim of this thesis is to contribute to control of paratuberculosis by investigating genetic variation in the pathogen and studying genetic variation in host susceptibility. Genetic variation of the pathogen was investigated within and between herds in the Netherlands. For host susceptibility to paratuberculosis, genetic variation and heritability were estimated for dairy cattle and dairy goats. For dairy cattle, results from the quantitative genetic analysis were used to perform a genome-wide association study to find chromosomal regions associated with susceptibility to disease. Finally, a genetic-epidemiological model was used to study the effect of genetic selection for increased resistance to paratuberculosis on the prevalence of infection in the dairy cattle population." @default.
- W37790948 created "2016-06-24" @default.
- W37790948 creator A5060087655 @default.
- W37790948 date "2012-12-06" @default.
- W37790948 modified "2023-09-27" @default.
- W37790948 title "Genetic variation in paratuberculosis in dairy populations" @default.
- W37790948 cites W144069059 @default.
- W37790948 cites W1502698740 @default.
- W37790948 cites W1531814879 @default.
- W37790948 cites W1546259622 @default.
- W37790948 cites W1546689440 @default.
- W37790948 cites W1563551186 @default.
- W37790948 cites W1576379183 @default.
- W37790948 cites W1824521948 @default.
- W37790948 cites W1853535253 @default.
- W37790948 cites W1911955222 @default.
- W37790948 cites W1963383323 @default.
- W37790948 cites W1968441196 @default.
- W37790948 cites W1969967451 @default.
- W37790948 cites W1974614840 @default.
- W37790948 cites W1974836016 @default.
- W37790948 cites W1975710274 @default.
- W37790948 cites W1976699124 @default.
- W37790948 cites W1977538419 @default.
- W37790948 cites W1981103205 @default.
- W37790948 cites W1982966394 @default.
- W37790948 cites W1983172005 @default.
- W37790948 cites W1985674242 @default.
- W37790948 cites W1990136487 @default.
- W37790948 cites W1991762982 @default.
- W37790948 cites W1994007191 @default.
- W37790948 cites W2000949885 @default.
- W37790948 cites W2001392251 @default.
- W37790948 cites W2002738458 @default.
- W37790948 cites W2007564903 @default.
- W37790948 cites W2011354398 @default.
- W37790948 cites W2012888273 @default.
- W37790948 cites W2013282427 @default.
- W37790948 cites W2018635815 @default.
- W37790948 cites W2019529058 @default.
- W37790948 cites W2019614759 @default.
- W37790948 cites W2020153499 @default.
- W37790948 cites W2022959497 @default.
- W37790948 cites W2023721614 @default.
- W37790948 cites W2027052333 @default.
- W37790948 cites W2030724014 @default.
- W37790948 cites W2034038159 @default.
- W37790948 cites W2034815849 @default.
- W37790948 cites W2041649518 @default.
- W37790948 cites W2042343594 @default.
- W37790948 cites W2045678063 @default.
- W37790948 cites W2047081999 @default.
- W37790948 cites W2047654536 @default.
- W37790948 cites W2049144280 @default.
- W37790948 cites W2056700641 @default.
- W37790948 cites W2057975876 @default.
- W37790948 cites W2058255506 @default.
- W37790948 cites W2059025151 @default.
- W37790948 cites W2060583076 @default.
- W37790948 cites W2061631212 @default.
- W37790948 cites W2066931725 @default.
- W37790948 cites W2067918660 @default.
- W37790948 cites W2068114983 @default.
- W37790948 cites W2071748269 @default.
- W37790948 cites W2073031900 @default.
- W37790948 cites W2075152199 @default.
- W37790948 cites W2077013584 @default.
- W37790948 cites W2077668635 @default.
- W37790948 cites W2078972251 @default.
- W37790948 cites W2080575519 @default.
- W37790948 cites W2080578928 @default.
- W37790948 cites W2081462201 @default.
- W37790948 cites W2083552945 @default.
- W37790948 cites W2085400701 @default.
- W37790948 cites W2088185802 @default.
- W37790948 cites W2092287543 @default.
- W37790948 cites W2092491128 @default.
- W37790948 cites W2093676490 @default.
- W37790948 cites W2095712614 @default.
- W37790948 cites W2098518235 @default.
- W37790948 cites W2098618245 @default.
- W37790948 cites W2098741870 @default.
- W37790948 cites W2100769490 @default.
- W37790948 cites W2101102916 @default.
- W37790948 cites W2104492326 @default.
- W37790948 cites W2105496771 @default.
- W37790948 cites W2107099195 @default.
- W37790948 cites W2107282357 @default.
- W37790948 cites W2107648723 @default.
- W37790948 cites W2107660742 @default.
- W37790948 cites W2108335201 @default.
- W37790948 cites W2109085886 @default.
- W37790948 cites W2109383738 @default.
- W37790948 cites W2109807863 @default.
- W37790948 cites W2110322110 @default.
- W37790948 cites W2110547774 @default.
- W37790948 cites W2110787179 @default.
- W37790948 cites W2110974472 @default.
- W37790948 cites W2115514643 @default.
- W37790948 cites W2117580564 @default.