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- W378397122 abstract "前治療のない肺小細胞癌32例を対象にAVP療法 (ADM 40mg/m2+VP-16 100mg/m2×3 days+CDDP 80mg/m2) を施行した. 評価可能30例中CRは6例 (20.0%), PR18例 (60.0%) で, 奏効率は80.0%(24/30) であった. またLD例のCR率は37.5%(3/8) で, 奏効率は100%(8/8) であり, ED例ではそれぞれ13.6%(3/22), 72.7%(16/22) であった. 生存期間中央値 (MST) に関しては全対象例で39.3週, LD例で60.7週, ED例で30.6週であった. またresponderのMSTは50.4週, non-responderのそれは30.6週であり, 両者間に有意差を認めた (p<0.05). grade3から4の白血球減少が23例 (76.7%) に, 血小板減少が9例 (30.0%) に認められ, grade2から3の食欲低下が25例 (83.3%), 悪心・嘔吐が21例 (70.0%), 脱毛が20例 (66.7%) に認められた. またgrade 2のGOT/GPTの上昇が1例 (3.3%) に, grade 2のクレアチニンの上昇が3例 (10.0%) に認められたが, いずれも特別の治療を要することなく改善した." @default.
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- W378397122 date "1993-01-01" @default.
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- W378397122 title "Combination Chemotherapy with Adriamycin, Etoposide and Cisplatin for Small Cell Lung Cancer." @default.
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- W378397122 doi "https://doi.org/10.2482/haigan.33.163" @default.
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