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- W380039804 abstract "The majority of research conducted in the field of streptococcal phages has concentrated on group A Streptococcus (GAS) phages. Therefore, the majority of this chapter reviews GAS phages. However, when pertinent, the chapter also discusses phages from group C Streptococcus (GCS) and group G Streptococcus (GGS). The results of comparative genomics described in this chapter have led to two predictions regarding the acquisition of phage-encoded virulence factors and GAS pathogenesis. First, it is the particular array of phage-encoded virulence factors, rather than simply the presence or absence of a single phage-encoded virulence factor, that significantly affects GAS pathogenesis by promoting the colonization of new hosts or the occupation of new biologic niches. Second, the complex pathogenesis of GAS is related to polylysogeny. Importantly, the genome sequences identified previously unknown phages and phage-encoded virulence factors, thereby raising the possibility that sequencing the genomes of additional GAS strains associated with specific clinical syndromes may identify additional novel phage-encoded virulence factors. Toxins and other virulence factors encoded by GAS phages can be divided into two main groups, including pyrogenic toxin superantigens (PTSAgs) and non-PTSAgs. It is well known that GAS prophages encode extracellular proteins that interact with the host during infection and contribute to pathogenesis. Only recently has the significant link between phage biology, genome diversity, and streptococcal pathogenesis been fully appreciated. Continued investigations of streptococcal phage biology will undoubtedly reveal additional significant contributions that these mobile genetic elements have in bacterial pathogenesis and human disease." @default.
- W380039804 created "2016-06-24" @default.
- W380039804 creator A5010204053 @default.
- W380039804 creator A5011540019 @default.
- W380039804 creator A5029885399 @default.
- W380039804 date "2014-04-30" @default.
- W380039804 modified "2023-09-23" @default.
- W380039804 title "Contribution of Phages to Group A Streptococcus Genetic Diversity and Pathogenesis" @default.
- W380039804 cites W111924924 @default.
- W380039804 cites W1484998934 @default.
- W380039804 cites W1505376259 @default.
- W380039804 cites W1657511054 @default.
- W380039804 cites W1852652523 @default.
- W380039804 cites W1895567516 @default.
- W380039804 cites W1934585871 @default.
- W380039804 cites W1963788281 @default.
- W380039804 cites W1969071924 @default.
- W380039804 cites W1971470851 @default.
- W380039804 cites W1974295442 @default.
- W380039804 cites W1976753545 @default.
- W380039804 cites W1977215128 @default.
- W380039804 cites W1980846005 @default.
- W380039804 cites W1981568487 @default.
- W380039804 cites W1982329864 @default.
- W380039804 cites W1991645878 @default.
- W380039804 cites W2004280494 @default.
- W380039804 cites W2006076492 @default.
- W380039804 cites W2007139752 @default.
- W380039804 cites W2011267212 @default.
- W380039804 cites W2014403739 @default.
- W380039804 cites W2014990493 @default.
- W380039804 cites W2024605876 @default.
- W380039804 cites W2025001119 @default.
- W380039804 cites W2026049658 @default.
- W380039804 cites W2027206556 @default.
- W380039804 cites W2028247608 @default.
- W380039804 cites W2029382724 @default.
- W380039804 cites W2030513019 @default.
- W380039804 cites W2035525902 @default.
- W380039804 cites W2047264619 @default.
- W380039804 cites W2052980621 @default.
- W380039804 cites W2059311311 @default.
- W380039804 cites W2061592501 @default.
- W380039804 cites W2075984312 @default.
- W380039804 cites W2076747646 @default.
- W380039804 cites W2078143666 @default.
- W380039804 cites W2080043237 @default.
- W380039804 cites W2083310795 @default.
- W380039804 cites W2086208676 @default.
- W380039804 cites W2090951253 @default.
- W380039804 cites W2093256465 @default.
- W380039804 cites W2095607618 @default.
- W380039804 cites W2097002929 @default.
- W380039804 cites W2107803884 @default.
- W380039804 cites W2110629361 @default.
- W380039804 cites W2114042701 @default.
- W380039804 cites W2121334867 @default.
- W380039804 cites W2123167146 @default.
- W380039804 cites W2125245605 @default.
- W380039804 cites W2127787621 @default.
- W380039804 cites W2128252987 @default.
- W380039804 cites W2130348108 @default.
- W380039804 cites W2132376418 @default.
- W380039804 cites W2132603632 @default.
- W380039804 cites W2133135013 @default.
- W380039804 cites W2137612277 @default.
- W380039804 cites W2141516076 @default.
- W380039804 cites W2142238456 @default.
- W380039804 cites W2144123881 @default.
- W380039804 cites W2144959128 @default.
- W380039804 cites W2144991205 @default.
- W380039804 cites W2145269008 @default.
- W380039804 cites W2147785780 @default.
- W380039804 cites W2150986328 @default.
- W380039804 cites W2151342725 @default.
- W380039804 cites W2152676793 @default.
- W380039804 cites W2154066176 @default.
- W380039804 cites W2154079711 @default.
- W380039804 cites W2155850138 @default.
- W380039804 cites W2161834179 @default.
- W380039804 cites W2162468551 @default.
- W380039804 cites W2162575803 @default.
- W380039804 cites W2165342530 @default.
- W380039804 cites W2166710365 @default.
- W380039804 cites W2171531154 @default.
- W380039804 cites W2292418154 @default.
- W380039804 cites W2323252911 @default.
- W380039804 cites W2326553598 @default.
- W380039804 cites W4211043921 @default.
- W380039804 cites W4245559833 @default.
- W380039804 cites W4319717423 @default.
- W380039804 cites W43350597 @default.
- W380039804 cites W635893080 @default.
- W380039804 doi "https://doi.org/10.1128/9781555816506.ch16" @default.
- W380039804 hasPublicationYear "2014" @default.
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