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• W38007478 abstract "Objectif : Decrire les phenotypes de resistance aux beta-lactamines des souches de Pseudomonas aeruginosa par la technique de l’antibiogramme en milieu gelose. Materiel et methode : Il s’agit d’une etude transversale realisee du 1 er septembre 2011 au 29 fevrier 2012 sur des souches de Pseudomonas aeruginosa isolees au laboratoire de bacteriologie medicale du CHU Sylvanus OLYMPIO. L’antibiogramme par la technique de diffusion en milieu gelose a ete realise pour la determination des phenotypes de resistance. Les disques « Ticarcilline + acide clavulanique (TCC) » Cefotaxime, Ceftazidime, Cefsulodine, Ticarcilline, Aztreonam et Imipeneme ont ete testes. L’interpretation de l’antibiogramme s’est faite selon les recommandations du Comite Antibiogramme de la societe francaise de Microbiologie. L’identification des phenotypes de resistance a ete operee selon la table proposee par Vedel et al. Resultats : Vingt-huit (28) isolats de Pseudomonas aeruginosa ont ete obtenus. Parmi eux 16 (57,1%) etaient d’origine communautaire et 12 (42,9%) etaient d’origine hospitaliere. Dix huit (64,3%) etaient de phenotype sauvage, 5 (17,9%) etaient de phenotype complexe, 2 (7,1%) etaient de phenotype BLSE, 2 (7,1%) etaient de phenotype cephalosporinases hyperproduites et 1 (3,6%) etait de phenotype impermeabilite specifique a l’Imipeneme ». Conclusion: L’identification des phenotypes de resistance de P.aeruginosa par la technique d’antibiogramme en milieu gelose constitue une alternative pour les laboratoires de bacteriologie medicale dans les pays aux ressources limitees comme le Togo, ou les techniques de biologie moleculaire ne sont pas disponibles pour la surveillance de la resistance aux antibiotiques et la prevention des infections nosocomiales. Mots cles : Antibiotiques, Phenotypes, Pseudomonas aeruginosa , resistance. Objective: Describe phenotypes pattern of susceptibility to beta-lactamines of clinicals strains of Pseudomonas aeruginosa by using agar plate method.  Methods: It is a cross-sectional study lead from 1 st September 2011 to 29 February 2012 on clinicals strains of Pseudomonas aeruginosa isolated at the laboratory of medical bacteriology CHU Sylvanus Olympio.The susceptibility test to antibiotics (Ticarcilline + clavulanic acid (TCC) » Cefotaxime, Ceftazidime, Cefsulodine, Ticarcilline, Aztreonam and Imipenem) were determined using paper disk diffusion method in well agar. The resultswereassessedusing the Comite Antibiogramme de la societe francaise de Microbiologie’recommandations. Identification of phenotype was made by using the table proposed by Vedel and al. Results: Twenty-eight (28) Pseudomonas aeruginos aclinicalsstrains were obtained during six months. Among them 16 (57.1%) were isolated from the community and 12 (42.9%) were nosocomial strains. Eighteen (64.3%) were wild-type phenotype, 5 (17.9%) were complex phenotype, 2 (7.1%) were ESBL phenotypes, 2(7.1%) were phenotype high level cephalosporinase and 1 (3.6%) was a phenotype with impermeability to imipenem. Conclusion: Antibiotics susceptibility testing by using agar plate method can be use in resources setting countries like Togo to survey bacteria resistance and to prevent nosocomial infection due to Pseudomonas aeruginosa . Keywords: Antibiotics, phenotype, Pseudomonas aeruginosa , susceptibility. Article in French" @default.
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• W38007478 date "2014-07-30" @default.
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• W38007478 title "Aspects Phenotypiques De La Resistance Aux Β- Lactamines Des Souches De Pseudomonas aeruginosa Isolees Au Laboratoire De Bacteriologie Medicale Du Chu Sylvanus Olympio (Chu So) De Lome, Togo." @default.
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