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• W384906195 abstract "The study of resting-state networks provides an informative paradigm for understanding the functional architecture of the human brain. Although investigating specialized resting-state networks has led to significant advances in our understanding of brain organization, the manner in which information is integrated across these networks remains unclear. Here, we have developed and validated a data-driven methodology for describing the topography of resting-state network convergence in the human brain. Our results demonstrate the importance of an ensemble of cortical and subcortical regions in supporting the convergence of multiple resting-state networks, including the rostral anterior cingulate, precuneus, posterior cingulate cortex, posterior parietal cortex, dorsal prefrontal cortex, along with the caudate head, anterior claustrum, and posterior thalamus. In addition, we have demonstrated a significant correlation between voxel-wise network convergence and global brain connectivity, emphasizing the importance of resting-state network convergence in facilitating global brain communication. Finally, we examined the convergence of systems within each of the individual resting-state networks in the brain, revealing the heterogeneity by which individual resting-state networks balance the competing demands of specialized processing against the integration of information. Together, our results suggest that the convergence of resting-state networks represents an important organizational principle underpinning systems-level integration in the human brain." @default.
• W384906195 created "2016-06-24" @default.
• W384906195 creator A5016156588 @default.
• W384906195 creator A5027933368 @default.
• W384906195 date "2015-11-01" @default.
• W384906195 modified "2023-10-04" @default.
• W384906195 title "Estimating Large-Scale Network Convergence in the Human Functional Connectome" @default.
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• W384906195 doi "https://doi.org/10.1089/brain.2015.0348" @default.
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