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- W38590145 abstract "Background:Patient recruitment to trials is problematic; many fail to achieve targets, leaving them underpowered and unable to address their hypothesis. Few solutions have been identified in existing literature. This thesis aimed to: identify factors associated with recruitment; andunderstand clinicians’ experiences of recruiting patients to a primary care based randomised controlled trial (RCT). This was explored using The Birmingham Atrial FibrillationTreatment of the Aged (BAFTA) trial as a case study.Methods:Mixed methods were used: a systematic review to identify factors influencing recruitment to primary care based RCTs; quantitative analysis of BAFTA data to identify factors associated with recruitment; and qualitative interviews with General Practitioners involved with BAFTA, to understand their experience of participation.Results:Existing literature demonstrated that influences on recruitment include: study workload; study question; concerns about patients. Recommendations to address these issues are not based on strong empirical evidence. BAFTA identified factors associated with patient recruitment(practice size; GP age; recruitment year); and patterns over time. Interviews identified differences in attitude between high and low recruiters, including risk perception and motivation.Conclusions:This thesis demonstrates how practitioners can influence patient recruitment. Revised recruitment methods need testing in prospective trials." @default.
- W38590145 created "2016-06-24" @default.
- W38590145 creator A5011253738 @default.
- W38590145 date "2012-07-01" @default.
- W38590145 modified "2023-09-27" @default.
- W38590145 title "An investigation of practice and practitioner factors that influence the recruitment of patients to primary care based randomised controlled trials: case study of the Birmingham Atrial Fibrillation Treatment of the Aged (BAFTA) study" @default.
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