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- W38604452 abstract "Lack of therapeutic options and poor reproducibility of histopathological subtypes have been the reasons that ovarian carcinomas are currently treated as monolithic entity. Histopathological grading is used to identify those patients who can be spared adjuvant therapy. With slight modifications of the WHO based subtype classification we have shown that subtypes (i.e. serous, endometrioid, clear cell, mucinous) can be reproducibly used to stratify patients according to disease-specific survival. As these pathologically identifiable subtypes have different epidemiologic and genetic risk factors, precursor lesions, molecular abnormalities and clinical behaviour, screening and management strategies have to be subtype-specific." @default.
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- W38604452 date "2008-08-17" @default.
- W38604452 modified "2023-10-02" @default.
- W38604452 title "Ovarialkarzinome" @default.
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- W38604452 doi "https://doi.org/10.1007/s00292-008-1028-9" @default.
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