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- W38752144 abstract "Approximately 15–20% of endogenous Cushing’s syndrome (CS) is secondary to adrenal gland disorders. Unilateral adrenocortical tumors (adenoma or carcinomas) are responsible for the majority of the cases of primary adrenal CS. Adrenocortical tumors are more common in the population above 50 years of age. Steroid-secreting adrenal tumors causing endocrine disease are rare, however, they correspond to 80% of all causes of ACTH-independent Cushing’s syndrome. The most common clinical presentation in adults is CS, contrasting with pediatric patients in whom virilization syndrome is more frequent. The incidence of adrenocortical carcinoma in the United States is estimated to be 0.2–0.4 per million population per year. Nevertheless, there is a high incidence of adrenocortical tumors in Southern and Southwestern region of Brazil, estimated to be approximately 10–15 times greater than the worldwide incidence. In this chapter, we review the clinical features, hormonal and imaging diagnosis, and treatment of ACTH-independent Cushing’s syndrome due to adrenocortical tumors." @default.
- W38752144 created "2016-06-24" @default.
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- W38752144 date "2010-01-01" @default.
- W38752144 modified "2023-10-18" @default.
- W38752144 title "ACTH-Independent Cushing’s Syndrome: Adrenocortical Tumors" @default.
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- W38752144 doi "https://doi.org/10.1007/978-1-60327-449-4_16" @default.
- W38752144 hasPublicationYear "2010" @default.
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