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- W387687532 abstract "A major hurdle to swine influenza vaccination of young piglets is maternal antibody interference. This interference is transient as it disappears when pigs reach about 3 months of age. We vaccinated piglets without and with interfering maternal antibody using a recombinant vector vaccine. In the absence of interfering maternal antibody, the vaccine was effective in inducing a strong immune response and greatly reduced the amount of virus. However, this same recombinant vaccine was not effective when interfering maternal antibodies were present. We are currently trying a higher dose of vaccine and different genes from SIV in hopes we can overcome this maternal antibody. Preliminary data from these new studies are promising." @default.
- W387687532 created "2016-06-24" @default.
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- W387687532 date "2009-01-01" @default.
- W387687532 modified "2023-09-25" @default.
- W387687532 title "Evaluation of a Virus-like Replicon Particle Vaccine Expressing Proteins of Swine Influenza Virus in Pigs With and Without Maternally Derived Antibodies" @default.
- W387687532 doi "https://doi.org/10.31274/ans_air-180814-644" @default.
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