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- W391271309 abstract "Using in vitro autoradiography, we investigated the effects of Kamikihito (KKT), a traditional Chinese medicine, on specific [3H]SCH23390 binding to dopamine D1 receptors and [3H]ketanserine binding to serotonin 5-HT2A receptors in the rat brain. Specific binding of both compounds was affected by aging. Long-term administration of KKT resulted in decreases in [3H]SCH23390 binding to the cortex and hippocampus in aged rats, and in decreases in [3H]ketanserine binding to the caudate/putamen in young rats. These results suggest that the changes in dopamine Di and serotonin 5-HT2A receptor binding may be involved in the central effects of KKT." @default.
- W391271309 created "2016-06-24" @default.
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- W391271309 date "1994-01-01" @default.
- W391271309 modified "2023-10-14" @default.
- W391271309 title "Effects of Kamikihito, a Traditional Chinese Medicine, on Neurotransmitter Receptor Binding in the Aged Rat Brain Determined byin Vitro Autoradiography: Changes in Dopamine D1 and Serotonin 5-HT2A Receptor Binding." @default.
- W391271309 doi "https://doi.org/10.1248/bpb.17.1132" @default.
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